Table 1.

Patient and graft characteristics (N = 44)

VariablesValue
Patient characteristics  
 Age, median (range), y 1.7 (0.4-16.6) 
 Weight, median (range), kg 12 (6-74) 
 Male sex, n (%) 27 (61) 
 Race, n (%)  
  White 29 (66) 
  African American 8 (18) 
  Hispanic 3 (7) 
  Asian 1 (2) 
  Alaska Native 1 (2) 
  2 or more races 2 (5) 
 Diagnosis, n (%)  
  Krabbe disease 13 (30) 
  Metachromatic leukodystrophy 7 (16) 
  Sickle cell disease 3 (7) 
  Gaucher disease 2 (5) 
  Hunter syndrome (MPS type II) 2 (5) 
  MHC class II deficiency 2 (5) 
  Osteopetrosis 2 (5) 
  XLP2 2 (5) 
  β-thalassemia 1 (2) 
  Cartilage-hair hypoplasia 1 (2) 
  Chédiak-Higashi syndrome 1 (2) 
  Combined immunodeficiency with multiple intestinal atresias 1 (2) 
  Diamond-Blackfan anemia 1 (2) 
  GM3 synthase deficiency 1 (2) 
  Hemophagocytic lymphohistiocytosis 1 (2) 
  Hurler syndrome (MPS type IH) 1 (2) 
  Severe congenital neutropenia 1 (2) 
  Tay-Sachs disease 1 (2) 
  X-linked adrenoleukodystrophy 1 (2) 
 CMV serostatus, seropositive 16 (36) 
Graft characteristics  
 HLA match (of 6), n (%)  
  6 16 (36) 
  5 19 (43) 
  4 9 (21) 
 HLA match (of 8), n (%)  
  8 8 (18) 
  7 10 (23) 
  6 14 (32) 
  5 10 (23) 
  4 2 (5) 
 TNC/kg, median (range), ×107 9.1 (2.3-24.8) 
 CD34/kg, median (range), ×105 3.31 (0.92-9.24) 
 Sex mismatch, n (%) 22 (50) 
 ABO mismatch, n (%) 28 (64) 
VariablesValue
Patient characteristics  
 Age, median (range), y 1.7 (0.4-16.6) 
 Weight, median (range), kg 12 (6-74) 
 Male sex, n (%) 27 (61) 
 Race, n (%)  
  White 29 (66) 
  African American 8 (18) 
  Hispanic 3 (7) 
  Asian 1 (2) 
  Alaska Native 1 (2) 
  2 or more races 2 (5) 
 Diagnosis, n (%)  
  Krabbe disease 13 (30) 
  Metachromatic leukodystrophy 7 (16) 
  Sickle cell disease 3 (7) 
  Gaucher disease 2 (5) 
  Hunter syndrome (MPS type II) 2 (5) 
  MHC class II deficiency 2 (5) 
  Osteopetrosis 2 (5) 
  XLP2 2 (5) 
  β-thalassemia 1 (2) 
  Cartilage-hair hypoplasia 1 (2) 
  Chédiak-Higashi syndrome 1 (2) 
  Combined immunodeficiency with multiple intestinal atresias 1 (2) 
  Diamond-Blackfan anemia 1 (2) 
  GM3 synthase deficiency 1 (2) 
  Hemophagocytic lymphohistiocytosis 1 (2) 
  Hurler syndrome (MPS type IH) 1 (2) 
  Severe congenital neutropenia 1 (2) 
  Tay-Sachs disease 1 (2) 
  X-linked adrenoleukodystrophy 1 (2) 
 CMV serostatus, seropositive 16 (36) 
Graft characteristics  
 HLA match (of 6), n (%)  
  6 16 (36) 
  5 19 (43) 
  4 9 (21) 
 HLA match (of 8), n (%)  
  8 8 (18) 
  7 10 (23) 
  6 14 (32) 
  5 10 (23) 
  4 2 (5) 
 TNC/kg, median (range), ×107 9.1 (2.3-24.8) 
 CD34/kg, median (range), ×105 3.31 (0.92-9.24) 
 Sex mismatch, n (%) 22 (50) 
 ABO mismatch, n (%) 28 (64) 

MHC, major histocompatibility complex; MPS, mucopolysaccharidosis; TNC, total nucleated cell; XLP2, X-linked lymphoproliferative syndrome type 2.