Selected univariable and multivariable analysis for relapse
| Factors . | SHR . | 95% CI . | P . |
|---|---|---|---|
| Univariable analysis for relapse | |||
| A-ME Ab HVG | 0.92 | 0.85-0.99 | .026 |
| A-ALL ME HVG | 0.96 | 0.93-0.99 | .006 |
| Class I-Ab HVG | 0.99 | 0.94-1.04 | .770 |
| Class I-ALL ME HVG | 0.99 | 0.97-1.02 | .668 |
| Class II-Ab ME HVG | 1.01 | 0.95-1.07 | .723 |
| Class II-ALL ME HVG | 1.00 | 0.98-1.02 | .903 |
| DP match/mismatch | |||
| Match | Ref | ||
| Permissive mismatch | 0.86 | 0.51-1.48 | .601 |
| Nonpermissive mismatch GVH | 0.25 | 0.09-0.76 | .014 |
| Nonpermissive mismatch HVG | 0.54 | 0.22-1.33 | .181 |
| Multivariable analysis for relapse* | |||
| A-ALL ME HVG (continuous) | 0.95 | 0.92-0.98 | .004 |
| Impact of DP match/mismatch | |||
| Match | Ref | ||
| Permissive mismatch | 0.74 | 0.42-1.30 | .302 |
| Nonpermissive mismatch GVH | 0.19 | 0.06-0.59 | .004 |
| Nonpermissive mismatch HVG | 0.54 | 0.19-1.52 | .247 |
| Factors . | SHR . | 95% CI . | P . |
|---|---|---|---|
| Univariable analysis for relapse | |||
| A-ME Ab HVG | 0.92 | 0.85-0.99 | .026 |
| A-ALL ME HVG | 0.96 | 0.93-0.99 | .006 |
| Class I-Ab HVG | 0.99 | 0.94-1.04 | .770 |
| Class I-ALL ME HVG | 0.99 | 0.97-1.02 | .668 |
| Class II-Ab ME HVG | 1.01 | 0.95-1.07 | .723 |
| Class II-ALL ME HVG | 1.00 | 0.98-1.02 | .903 |
| DP match/mismatch | |||
| Match | Ref | ||
| Permissive mismatch | 0.86 | 0.51-1.48 | .601 |
| Nonpermissive mismatch GVH | 0.25 | 0.09-0.76 | .014 |
| Nonpermissive mismatch HVG | 0.54 | 0.22-1.33 | .181 |
| Multivariable analysis for relapse* | |||
| A-ALL ME HVG (continuous) | 0.95 | 0.92-0.98 | .004 |
| Impact of DP match/mismatch | |||
| Match | Ref | ||
| Permissive mismatch | 0.74 | 0.42-1.30 | .302 |
| Nonpermissive mismatch GVH | 0.19 | 0.06-0.59 | .004 |
| Nonpermissive mismatch HVG | 0.54 | 0.19-1.52 | .247 |
*Impact of HLA eplet mismatch on each locus on relapse was analyzed in separate models, adjusted for sex, age, HCT-CI, DRI, transplant protocol, conditioning regimen intensity, donor relation, stem cell source, and ABO match. Impacts of these covariates are not shown.