Selected univariable and multivariable analysis for PFS
| Factors . | HR . | 95% CI . | P . |
|---|---|---|---|
| Univariable analysis for PFS | |||
| A-ME Ab HVG | 0.93 | 0.89-0.98 | .007 |
| A-ALL ME HVG | 0.97 | 0.95-0.99 | .003 |
| Class I-Ab ME HVG | 0.97 | 0.94-1.00 | .091 |
| Class I-ALL ME HVG | 0.09 | 0.97-0.99 | .032 |
| Class II-Ab ME HVG | 1.03 | 0.99-1.07 | .155 |
| Class II-ALL ME HVG | 1.01 | 0.99-1.03 | .050 |
| DP match/mismatch | |||
| Match | Ref | ||
| Permissive mismatch | 0.66 | 0.45-0.96 | .034 |
| Nonpermissive mismatch GVH | 0.66 | 0.39-1.11 | .120 |
| Nonpermissive mismatch HVG | 0.59 | 0.32-1.07 | .084 |
| Multivariable analysis for PFS* | |||
| A-ALL ME HVG (continuous) | 0.96 | 0.05-0.98 | <.001 |
| Class I-ALL ME HVG (continuous) | 0.98 | 0.97-0.99 | .039 |
| Impact of DP match/mismatch | |||
| Match | Ref | ||
| Permissive mismatch | 0.66 | 0.45-0.98 | .040 |
| Nonpermissive mismatch GVH | 0.64 | 0.37-1.10 | .110 |
| Nonpermissive mismatch HVG | 0.66 | 0.36-1.24 | .202 |
| HLA Class II-ALL ME HVG (continuous) | 1.01 | 0.99-1.02 | .107 |
| Factors . | HR . | 95% CI . | P . |
|---|---|---|---|
| Univariable analysis for PFS | |||
| A-ME Ab HVG | 0.93 | 0.89-0.98 | .007 |
| A-ALL ME HVG | 0.97 | 0.95-0.99 | .003 |
| Class I-Ab ME HVG | 0.97 | 0.94-1.00 | .091 |
| Class I-ALL ME HVG | 0.09 | 0.97-0.99 | .032 |
| Class II-Ab ME HVG | 1.03 | 0.99-1.07 | .155 |
| Class II-ALL ME HVG | 1.01 | 0.99-1.03 | .050 |
| DP match/mismatch | |||
| Match | Ref | ||
| Permissive mismatch | 0.66 | 0.45-0.96 | .034 |
| Nonpermissive mismatch GVH | 0.66 | 0.39-1.11 | .120 |
| Nonpermissive mismatch HVG | 0.59 | 0.32-1.07 | .084 |
| Multivariable analysis for PFS* | |||
| A-ALL ME HVG (continuous) | 0.96 | 0.05-0.98 | <.001 |
| Class I-ALL ME HVG (continuous) | 0.98 | 0.97-0.99 | .039 |
| Impact of DP match/mismatch | |||
| Match | Ref | ||
| Permissive mismatch | 0.66 | 0.45-0.98 | .040 |
| Nonpermissive mismatch GVH | 0.64 | 0.37-1.10 | .110 |
| Nonpermissive mismatch HVG | 0.66 | 0.36-1.24 | .202 |
| HLA Class II-ALL ME HVG (continuous) | 1.01 | 0.99-1.02 | .107 |
*Impact of HLA eplet mismatch on each locus on PFS was analyzed in separate models, adjusted for sex, age, HCT-CI, DRI, transplant protocol, conditioning regimen intensity, donor relation, stem cell source, and ABO match. Impacts of these covariates are not shown.