Delivery outcomes in women with VWD at delivery by treatment group
| Variable . | rVWF (n = 6) . | pdVWF (n = 6) . | P . |
|---|---|---|---|
| Delivery (vaginal vs cesarean) | 3/6 (50.0) | 4/6 (66.7) | 1.000 |
| Anesthesia (any vs none) | 5/6 (83.3) | 6/6 (100) | 1.000 |
| EBL, mL | |||
| All patients | .384 | ||
| Median | 685 | 462 | |
| IQR | 525-942 | 362-806 | |
| Vaginal delivery | .722 | ||
| Median | 500 | 375 | |
| IQR | 350-550 | 325-431 | |
| Cesarean delivery | .531 | ||
| Median | 1000 | 950 | |
| IQR | 885-1375 | 925-975 | |
| PPH (yes vs no) | |||
| All patients | 2/6 (33.3) | 1/6 (16.7) | 1.000 |
| Vaginal delivery | 1/3 (33.3) | 1/4 (25.0) | 1.000 |
| Cesarean delivery | 1/3 (33.3) | 0/2 (0) | 1.000 |
| Hemoglobin at delivery, g/dL | .845 | ||
| Median | 11.9 | 11.6 | |
| IQR | 10.7-12.7 | 11.1-12.7 | |
| Platelet count at delivery, × 103/μL | .618 | ||
| Median | 177 | 185 | |
| IQR | 150-238 | 174-326 | |
| VWF dose of 80 UI/kg/d | 6/6 (100) | 6/6 (100) | 1.000 |
| Transfusion after delivery, RBCs | 0/6 (0) | 0/6 (0) | 1.000 |
| Complications (yes vs no) | |||
| Any | 3/6 (50.0) | 2/6 (33.3) | 1.000 |
| Preeclampsia | 2/6 (33.3) | 0/6 (0) | 1.000 |
| HELLP syndrome | 0/6 (0) | 1/6 (16.7) | 1.000 |
| Uterine atony | 1/6 (16.7) | 0/6 (0) | 1.000 |
| 1° or 2° perineal tear | 1/6 (16.7) | 3/6 (50.0) | .545 |
| Length of hospital stay, d | .078 | ||
| Median | 4.0 | 2.5 | |
| IQR | 3.2-4.0 | 2.0-3.7 | |
| Payer (private vs Medicaid) | 6/6 (100) | 4/6 (66.7) | .455 |
| Variable . | rVWF (n = 6) . | pdVWF (n = 6) . | P . |
|---|---|---|---|
| Delivery (vaginal vs cesarean) | 3/6 (50.0) | 4/6 (66.7) | 1.000 |
| Anesthesia (any vs none) | 5/6 (83.3) | 6/6 (100) | 1.000 |
| EBL, mL | |||
| All patients | .384 | ||
| Median | 685 | 462 | |
| IQR | 525-942 | 362-806 | |
| Vaginal delivery | .722 | ||
| Median | 500 | 375 | |
| IQR | 350-550 | 325-431 | |
| Cesarean delivery | .531 | ||
| Median | 1000 | 950 | |
| IQR | 885-1375 | 925-975 | |
| PPH (yes vs no) | |||
| All patients | 2/6 (33.3) | 1/6 (16.7) | 1.000 |
| Vaginal delivery | 1/3 (33.3) | 1/4 (25.0) | 1.000 |
| Cesarean delivery | 1/3 (33.3) | 0/2 (0) | 1.000 |
| Hemoglobin at delivery, g/dL | .845 | ||
| Median | 11.9 | 11.6 | |
| IQR | 10.7-12.7 | 11.1-12.7 | |
| Platelet count at delivery, × 103/μL | .618 | ||
| Median | 177 | 185 | |
| IQR | 150-238 | 174-326 | |
| VWF dose of 80 UI/kg/d | 6/6 (100) | 6/6 (100) | 1.000 |
| Transfusion after delivery, RBCs | 0/6 (0) | 0/6 (0) | 1.000 |
| Complications (yes vs no) | |||
| Any | 3/6 (50.0) | 2/6 (33.3) | 1.000 |
| Preeclampsia | 2/6 (33.3) | 0/6 (0) | 1.000 |
| HELLP syndrome | 0/6 (0) | 1/6 (16.7) | 1.000 |
| Uterine atony | 1/6 (16.7) | 0/6 (0) | 1.000 |
| 1° or 2° perineal tear | 1/6 (16.7) | 3/6 (50.0) | .545 |
| Length of hospital stay, d | .078 | ||
| Median | 4.0 | 2.5 | |
| IQR | 3.2-4.0 | 2.0-3.7 | |
| Payer (private vs Medicaid) | 6/6 (100) | 4/6 (66.7) | .455 |
Data are n (%), except continuous data are reported as median (interquartile range [IQR]) with 95% confidence intervals.