Characteristics of women with VWD by treatment group
| Variable . | rVWF (n = 6) . | pdVWF (n = 6) . | P . |
|---|---|---|---|
| Type of VWD | |||
| 1 vs 2/3 | 5/6 (83.3) | 6/6 (100) | 1.000 |
| Age, y | .075 | ||
| Median | 32 | 27 | |
| IQR | 30.5-34.2 | 22.7-30.5 | |
| Race | |||
| White/African American | 6/6 (100) | 4/6 (66.7) | .455 |
| Blood type | |||
| O vs A, B, AB | 5/6 (83.3) | 4/6 (66.7) | 1.000 |
| Baseline bleeding score | .734 | ||
| Median | 3.0 | 3.5 | |
| IQR | 3.0-4.5 | 2.25-4.0 | |
| Bleeding history | |||
| Bruising | 5/6 (83.3) | 5/6 (83.3) | 1.000 |
| Dental bleeding | 3/6 (50.0) | 1/6 (16.7) | .545 |
| Epistaxis | 5/6 (83.3) | 3/6 (50.0) | .545 |
| Hematoma | 0/6 (0) | 1/6 (16.7) | 1.000 |
| Menorrhagia | 5/6 (83.3) | 4/6 (66.7) | 1.000 |
| Postoperative bleeding | 2/6 (33.3) | 2/6 (33.3) | 1.000 |
| Postpartum bleeding | 1/6 (16.7) | 0/6 (0) | 1.000 |
| Comorbidity | |||
| Anemia | 2/6 (33.3) | 0/6 (0) | .455 |
| Diabetes | 1/6 (16.7) | 0/6 (0) | 1.000 |
| Hypertension | 0/6 (0) | 1/6 (16.7) | 1.000 |
| Obesity (BMI >30 kg/m2) | 4/6 (66.7) | 4/6 (66.7) | 1.000 |
| Smoking | 0/6 (0) | 1/6 (0) | 1.000 |
| BMI, kg/m2 | |||
| Baseline | .691 | ||
| Median | 29.0 | 29.2 | |
| IQR | 27.7-29.4 | 23.7-32.4 | |
| Month 8 | .799 | ||
| Median | 32.2 | 35.1 | |
| IQR | 30.5-34.5 | 28.0-36.1 | |
| Delivery | .887 | ||
| Median | 33.8 | 36.6 | |
| IQR | 32.2-35.5 | 30.0-38.8 | |
| VWF/RCo, IU/mL | |||
| Baseline | .650 | ||
| Median | 0.44 | 0.55 | |
| IQR | 0.29-0.57 | 0.32-0.62 | |
| Month 8 | .243 | ||
| Median | 0.81 | 1.29 | |
| IQR | 0.61-1.23 | 0.94-1.59 | |
| VWF/Ag, IU/mL | |||
| Baseline | .430 | ||
| Median | 0.51 | 0.74 | |
| IQR | 0.45-0.55 | 0.48-0.81 | |
| Month 8 | .437 | ||
| Median | 1.12 | 1.92 | |
| IQR | 0.92-1.62 | 1.41-2.10 | |
| VIII/C, IU/mL | |||
| Baseline | .258 | ||
| Median | 0.73 | 0.92 | |
| IQR | 0.65-0.75 | 0.60-1.09 | |
| Month 8 | .335 | ||
| Median | 1.66 | 1.95 | |
| IQR | 1.37-1.92 | 1.46-2.63 |
| Variable . | rVWF (n = 6) . | pdVWF (n = 6) . | P . |
|---|---|---|---|
| Type of VWD | |||
| 1 vs 2/3 | 5/6 (83.3) | 6/6 (100) | 1.000 |
| Age, y | .075 | ||
| Median | 32 | 27 | |
| IQR | 30.5-34.2 | 22.7-30.5 | |
| Race | |||
| White/African American | 6/6 (100) | 4/6 (66.7) | .455 |
| Blood type | |||
| O vs A, B, AB | 5/6 (83.3) | 4/6 (66.7) | 1.000 |
| Baseline bleeding score | .734 | ||
| Median | 3.0 | 3.5 | |
| IQR | 3.0-4.5 | 2.25-4.0 | |
| Bleeding history | |||
| Bruising | 5/6 (83.3) | 5/6 (83.3) | 1.000 |
| Dental bleeding | 3/6 (50.0) | 1/6 (16.7) | .545 |
| Epistaxis | 5/6 (83.3) | 3/6 (50.0) | .545 |
| Hematoma | 0/6 (0) | 1/6 (16.7) | 1.000 |
| Menorrhagia | 5/6 (83.3) | 4/6 (66.7) | 1.000 |
| Postoperative bleeding | 2/6 (33.3) | 2/6 (33.3) | 1.000 |
| Postpartum bleeding | 1/6 (16.7) | 0/6 (0) | 1.000 |
| Comorbidity | |||
| Anemia | 2/6 (33.3) | 0/6 (0) | .455 |
| Diabetes | 1/6 (16.7) | 0/6 (0) | 1.000 |
| Hypertension | 0/6 (0) | 1/6 (16.7) | 1.000 |
| Obesity (BMI >30 kg/m2) | 4/6 (66.7) | 4/6 (66.7) | 1.000 |
| Smoking | 0/6 (0) | 1/6 (0) | 1.000 |
| BMI, kg/m2 | |||
| Baseline | .691 | ||
| Median | 29.0 | 29.2 | |
| IQR | 27.7-29.4 | 23.7-32.4 | |
| Month 8 | .799 | ||
| Median | 32.2 | 35.1 | |
| IQR | 30.5-34.5 | 28.0-36.1 | |
| Delivery | .887 | ||
| Median | 33.8 | 36.6 | |
| IQR | 32.2-35.5 | 30.0-38.8 | |
| VWF/RCo, IU/mL | |||
| Baseline | .650 | ||
| Median | 0.44 | 0.55 | |
| IQR | 0.29-0.57 | 0.32-0.62 | |
| Month 8 | .243 | ||
| Median | 0.81 | 1.29 | |
| IQR | 0.61-1.23 | 0.94-1.59 | |
| VWF/Ag, IU/mL | |||
| Baseline | .430 | ||
| Median | 0.51 | 0.74 | |
| IQR | 0.45-0.55 | 0.48-0.81 | |
| Month 8 | .437 | ||
| Median | 1.12 | 1.92 | |
| IQR | 0.92-1.62 | 1.41-2.10 | |
| VIII/C, IU/mL | |||
| Baseline | .258 | ||
| Median | 0.73 | 0.92 | |
| IQR | 0.65-0.75 | 0.60-1.09 | |
| Month 8 | .335 | ||
| Median | 1.66 | 1.95 | |
| IQR | 1.37-1.92 | 1.46-2.63 |
Data are n (%), except continuous data are reported as median (interquartile range [IQR]) with 95% confidence intervals.
Ag, antigen; BMI, body mass index.