Table 2.

Criteria for histological analysis of immune-mediated toxicity

Organ siteCriteria for immune-mediated toxicity
Liver Inflammatory foci, hepatocyte injury 
Small intestine/colon Immune infiltrate, shortened villi, denuded mucosa 
Organ siteCriteria for immune-mediated toxicity
Liver Inflammatory foci, hepatocyte injury 
Small intestine/colon Immune infiltrate, shortened villi, denuded mucosa 
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