Baseline characteristics and outcomes of the study population
| . | Total population (N = 3772) . | No AC or antiplatelets (n = 2859) . | AC (n = 241) . | Antiplatelets (n = 672) . | P . |
|---|---|---|---|---|---|
| Age, mean (SD), y | 56.6 (18.2) | 52.36 (17.6) | 73.25 (13.6) | 68.77 (12.4) | <.001 |
| Males | 2067 (54.8) | 1533 (53.6) | 133 (55.2) | 401 (59.7) | .018 |
| Race | |||||
| NHW | 1036 (27.5) | 792 (27.7) | 89 (36.9) | 155 (23.1) | <.001 |
| NHB | 979 (25.9) | 712 (24.9) | 69 (28.7) | 198 (29.5) | |
| Other | 1540 (40.8) | 1186 (41.5) | 68 (28.2) | 286 (42.5) | |
| Unknown | 217 (5.8) | 169 (5.9) | 15 (6.2) | 33 (4.9) | |
| CCI, mean (SD) | 1.13 (1.78) | 0.67 (1.34) | 2.96 (2.48) | 2.45 (2.03) | <.001 |
| Lung disease | 562 (14.9) | 392 (13.7) | 52 (21.6) | 118 (17.6) | <.001 |
| Obesity | 1066 (28.3) | 740 (25.9) | 89 (36.9) | 237 (35.3) | <.001 |
| Current smoker | 155 (4.1) | 115 (4.0) | 11 (4.6) | 29 (4.3) | <.001 |
| Prior VTE | 123 (3.3) | 38 (1.3) | 64 (26.6) | 21 (3.2) | <.001 |
| All-cause mortality | 567 (15.0) | 317 (11.1) | 81 (33.6) | 169 (25.2) | <.001 |
| Intubation-mechanical ventilation | 519 (13.8) | 332 (11.6) | 57 (23.7) | 130 (19.4) | <.001 |
| Hospital admission | 2031 (53.8) | 1321 (46.2) | 200 (83.0) | 510 (75.9) | <.001 |
| New RRT | 132 (3.5) | 91 (3.2) | 7 (2.9) | 34 (5.1) | .051 |
| Overt thrombosis | 46 (1.2) | 29 (1.0) | 3 (1.2) | 14 (2.1) | .076 |
| Major bleeding | 23 (0.6) | 11 (0.4) | 3 (1.2) | 9 (1.3) | .007 |
| . | Total population (N = 3772) . | No AC or antiplatelets (n = 2859) . | AC (n = 241) . | Antiplatelets (n = 672) . | P . |
|---|---|---|---|---|---|
| Age, mean (SD), y | 56.6 (18.2) | 52.36 (17.6) | 73.25 (13.6) | 68.77 (12.4) | <.001 |
| Males | 2067 (54.8) | 1533 (53.6) | 133 (55.2) | 401 (59.7) | .018 |
| Race | |||||
| NHW | 1036 (27.5) | 792 (27.7) | 89 (36.9) | 155 (23.1) | <.001 |
| NHB | 979 (25.9) | 712 (24.9) | 69 (28.7) | 198 (29.5) | |
| Other | 1540 (40.8) | 1186 (41.5) | 68 (28.2) | 286 (42.5) | |
| Unknown | 217 (5.8) | 169 (5.9) | 15 (6.2) | 33 (4.9) | |
| CCI, mean (SD) | 1.13 (1.78) | 0.67 (1.34) | 2.96 (2.48) | 2.45 (2.03) | <.001 |
| Lung disease | 562 (14.9) | 392 (13.7) | 52 (21.6) | 118 (17.6) | <.001 |
| Obesity | 1066 (28.3) | 740 (25.9) | 89 (36.9) | 237 (35.3) | <.001 |
| Current smoker | 155 (4.1) | 115 (4.0) | 11 (4.6) | 29 (4.3) | <.001 |
| Prior VTE | 123 (3.3) | 38 (1.3) | 64 (26.6) | 21 (3.2) | <.001 |
| All-cause mortality | 567 (15.0) | 317 (11.1) | 81 (33.6) | 169 (25.2) | <.001 |
| Intubation-mechanical ventilation | 519 (13.8) | 332 (11.6) | 57 (23.7) | 130 (19.4) | <.001 |
| Hospital admission | 2031 (53.8) | 1321 (46.2) | 200 (83.0) | 510 (75.9) | <.001 |
| New RRT | 132 (3.5) | 91 (3.2) | 7 (2.9) | 34 (5.1) | .051 |
| Overt thrombosis | 46 (1.2) | 29 (1.0) | 3 (1.2) | 14 (2.1) | .076 |
| Major bleeding | 23 (0.6) | 11 (0.4) | 3 (1.2) | 9 (1.3) | .007 |
Unless otherwise noted, all data are n (%).
CCI, Charlson Comorbidity Index; NHB, non-Hispanic black; NHW, non-Hispanic white; RRT, renal replacement therapy; SD, standard deviation; VTE, venous thromboembolism.