Correlation between UCHL1, MYC, and MYC-target genes in B-cell lymphoma
| Data set . | Correlation (r) MYC:UCHL1 . | Z score MYC-targets V1 (UCHL1HI/LO) . | Z score MYC-targets V1 (UCHL1HI/LO; MYC NL) . |
|---|---|---|---|
| GSE4475 | 0.338* | 16.13 | 11.471† |
| GSE87371 | 0.003 | 12.32 | 11.03 |
| GSE10846 | 0.273* | 10.34 | 10.91 |
| GSE31312 | 0.067 | 9.06 | 4.13 |
| GSE57611 | −0.043 | 12.85 | 13.53 |
| Data set . | Correlation (r) MYC:UCHL1 . | Z score MYC-targets V1 (UCHL1HI/LO) . | Z score MYC-targets V1 (UCHL1HI/LO; MYC NL) . |
|---|---|---|---|
| GSE4475 | 0.338* | 16.13 | 11.471† |
| GSE87371 | 0.003 | 12.32 | 11.03 |
| GSE10846 | 0.273* | 10.34 | 10.91 |
| GSE31312 | 0.067 | 9.06 | 4.13 |
| GSE57611 | −0.043 | 12.85 | 13.53 |
Analyzed with the R2: Genomics Analysis and Visualization Platform (http://r2.amc.nl). Z scores calculated for MSigDB Hallmark Geneset using PAGE. UCHL1 HI defined as 80th-100th percentile UCHL1 expression. MYC normal (NL) defined as 0-80th percentile.
Significance for correlation P < .05.
MYC rearrangements were excluded.