Table 1.

Ex vivo sensitivity of primary myeloma cells to BH3 mimetics

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BCL2, BCLXL, and MCL1 dependencies were defined as indicated in Figure 1B (red, high; orange, intermediate, green, not dependent). Molecular groups were determined either by fluorescence in situ hybridization or by quantitative polymerase chain reaction gene expression of anchorage genes of each molecular subgroup in purified CD138+ myeloma cells as defined in supplemental Table 1. Diag, diagnosis; F, female; M, male; NA, data not available; ns, nonsecreting; PC, plasma cells; Rel, relapse.

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