Driver mutations found in AL
| Gene . | Number of mutations . | Number of patients . | Variants . |
|---|---|---|---|
| DIS3 | 2 | 1 | D479E, M667L |
| DUSP2 | 1 | 1 | Splice donor variant |
| EGR1 | 1 | 1 | Q95R |
| EP300 | 1 | 1 | I997V |
| IRF4 | 1 | 1 | S332G |
| KLHL6 | 1 | 1 | V337M |
| KMT2B | 1 | 1 | P204H |
| NRAS | 2 | 2 | Q61R; Q61H |
| SAMHD1 | 1 | 1 | F363L |
| TET2 | 1 | 1 | P363L |
| TRAF3 | 1 | 1 | Splice donor variant |
| ZFP36L1 | 1 | 1 | L82S |
| ZNF292 | 1 | 1 | I1740V |
| Gene . | Number of mutations . | Number of patients . | Variants . |
|---|---|---|---|
| DIS3 | 2 | 1 | D479E, M667L |
| DUSP2 | 1 | 1 | Splice donor variant |
| EGR1 | 1 | 1 | Q95R |
| EP300 | 1 | 1 | I997V |
| IRF4 | 1 | 1 | S332G |
| KLHL6 | 1 | 1 | V337M |
| KMT2B | 1 | 1 | P204H |
| NRAS | 2 | 2 | Q61R; Q61H |
| SAMHD1 | 1 | 1 | F363L |
| TET2 | 1 | 1 | P363L |
| TRAF3 | 1 | 1 | Splice donor variant |
| ZFP36L1 | 1 | 1 | L82S |
| ZNF292 | 1 | 1 | I1740V |