Table 2.

The effects of HLA-DRB1*08:03 on laboratory test results in patients with iTTP in the acute phase

HLA-DRB1*08:03
Positive (n = 16)Negative (n = 36)P
ADAMTS13 activity (%) <0.5 (<0.5-<0.5) <0.5 (<0.5-<0.5) .766 
ADAMTS13 inhibitor (BU/mL) 3.15 (1.78-4.65) 2.0 (1.0-3.5) .254 
Platelet count (109/L) 15.5 (7.0-32.3) 11.0 (9.0-14.0) .211 
Hemoglobin (g/dL) 7.95 (6.93-9.63) 8.0 (7.2-9.3) .873 
LDH (U/L) 742 (509-965) 1138 (725-1598) .017 
Total bilirubin (mg/dL) 2.25 (1.2-2.43) 3.3 (2.2-4.9) .015 
Serum creatine (mg/dL) 0.8 (0.68-0.9) 1.0 (0.7-1.1) .103 
HLA-DRB1*08:03
Positive (n = 16)Negative (n = 36)P
ADAMTS13 activity (%) <0.5 (<0.5-<0.5) <0.5 (<0.5-<0.5) .766 
ADAMTS13 inhibitor (BU/mL) 3.15 (1.78-4.65) 2.0 (1.0-3.5) .254 
Platelet count (109/L) 15.5 (7.0-32.3) 11.0 (9.0-14.0) .211 
Hemoglobin (g/dL) 7.95 (6.93-9.63) 8.0 (7.2-9.3) .873 
LDH (U/L) 742 (509-965) 1138 (725-1598) .017 
Total bilirubin (mg/dL) 2.25 (1.2-2.43) 3.3 (2.2-4.9) .015 
Serum creatine (mg/dL) 0.8 (0.68-0.9) 1.0 (0.7-1.1) .103 

Median (25%-75%).

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