RAMs for VTE and bleeding
| Risk factors . | OR (95% CI) from systematic review . | β coefficients (log OR) . | SE . | Contribution to overall risk, % . |
|---|---|---|---|---|
| VTE | ||||
| Age >60 y | 1.34 (1.17-1.55) | 0.29 | 0.07 | 3.6 |
| Previous VTE | 6.08 (3.71-9.97) | 1.81 | 0.25 | 22.7 |
| Acute infections | 1.48 (1.16-1.89) | 0.39 | 0.12 | 4.9 |
| Immobility | 3.17 (2.18-4.62) | 1.15 | 0.19 | 14.4 |
| Acute paresis | 2.97 (1.20-7.36) | 1.09 | 0.46 | 13.6 |
| Active malignancy | 2.65 (1.79-3.91) | 0.98 | 0.20 | 12.3 |
| Critical illness | 1.65 (1.39-1.95) | 0.50 | 0.09 | 6.3 |
| Known history of thrombophilia | 5.88 (2.80-12.35) | 1.77 | 0.38 | 22.2 |
| Total | 7.98 | |||
| Bleeding | ||||
| Age ≥65 y | 1.95 (1.59-2.38) | 0.67 | 0.10 | 12.3 |
| Renal failure | 1.43 (1.06-1.93) | 0.36 | 0.15 | 6.6 |
| Thrombocytopenia | 1.79 (0.97-3.29) | 0.58 | 0.31 | 10.7 |
| Active gastroduodenal ulcers | 2.74 (1.42-5.26) | 1.01 | 0.34 | 18.6 |
| Hepatic disease | 1.53 (1.09-2.15) | 0.43 | 0.17 | 7.9 |
| Recent bleeding | 5.15 (2.45-10.81) | 1.64 | 0.38 | 30.2 |
| Critical illness | 2.10 (1.42-3.11) | 0.74 | 0.20 | 13.7 |
| Total | 5.43 | |||
| Risk factors . | OR (95% CI) from systematic review . | β coefficients (log OR) . | SE . | Contribution to overall risk, % . |
|---|---|---|---|---|
| VTE | ||||
| Age >60 y | 1.34 (1.17-1.55) | 0.29 | 0.07 | 3.6 |
| Previous VTE | 6.08 (3.71-9.97) | 1.81 | 0.25 | 22.7 |
| Acute infections | 1.48 (1.16-1.89) | 0.39 | 0.12 | 4.9 |
| Immobility | 3.17 (2.18-4.62) | 1.15 | 0.19 | 14.4 |
| Acute paresis | 2.97 (1.20-7.36) | 1.09 | 0.46 | 13.6 |
| Active malignancy | 2.65 (1.79-3.91) | 0.98 | 0.20 | 12.3 |
| Critical illness | 1.65 (1.39-1.95) | 0.50 | 0.09 | 6.3 |
| Known history of thrombophilia | 5.88 (2.80-12.35) | 1.77 | 0.38 | 22.2 |
| Total | 7.98 | |||
| Bleeding | ||||
| Age ≥65 y | 1.95 (1.59-2.38) | 0.67 | 0.10 | 12.3 |
| Renal failure | 1.43 (1.06-1.93) | 0.36 | 0.15 | 6.6 |
| Thrombocytopenia | 1.79 (0.97-3.29) | 0.58 | 0.31 | 10.7 |
| Active gastroduodenal ulcers | 2.74 (1.42-5.26) | 1.01 | 0.34 | 18.6 |
| Hepatic disease | 1.53 (1.09-2.15) | 0.43 | 0.17 | 7.9 |
| Recent bleeding | 5.15 (2.45-10.81) | 1.64 | 0.38 | 30.2 |
| Critical illness | 2.10 (1.42-3.11) | 0.74 | 0.20 | 13.7 |
| Total | 5.43 | |||
SE, standard error.