Table 1. Risk factors from empirical... | American Society of Hematology

Table 1.

Risk factors from empirical evidence and panel input for the outcomes VTE and bleeding

Source	Risk factors
VTE
Included studies in the systematic review	1. Age >60 y	16. Known history of thrombophilia
	2. Sex	17. Thrombocytosis
	3. Previous VTE	18. Central venous catheter use
	4. Acute infection	19. Varicose veins
	5. Respiratory failure	20. Leg edema
	6. Renal failure	21. Tobacco
	7. Immobility*	22. Coronary artery disease
	8. Acute paresis*	23. Heart failure
	9. Severe stroke	24. Fever
	10. Malignancy	25. Elevated heart rate
	11. Critical illness*	26. Leukocytosis
	12. D-dimer	27. Low Barthel index score
	13. Autoimmune disease	28. Elevated C-reactive protein
	14. Obesity	29. Fibrinogen levels
	15. Hormone use	29. Fibrinogen levels
Panel input	1. Recent surgery <30 d before admission
	2. Recent long bone fractures
	3. Recent air travel
Bleeding
Included studies in the systematic review	1. Age ≥65 y	10. CVC use
	2. Sex	11. Active gastroduodenal ulcers in past 3 mo
	3. Renal failure	12. Hepatic disease
	4. Malignancy	13. Antithrombotic medication use†
	5. Critical illness	14. Rehospitalization†
	6. Autoimmune disease	15. Blood dyscrasias
	7. Obesity	16. Recent bleeding
	8. Hormone use	17. Low hemoglobin
	9. Thrombocytopenia	17. Low hemoglobin
Panel input	None

Source	Risk factors
VTE
Included studies in the systematic review	1. Age >60 y	16. Known history of thrombophilia
	2. Sex	17. Thrombocytosis
	3. Previous VTE	18. Central venous catheter use
	4. Acute infection	19. Varicose veins
	5. Respiratory failure	20. Leg edema
	6. Renal failure	21. Tobacco
	7. Immobility*	22. Coronary artery disease
	8. Acute paresis*	23. Heart failure
	9. Severe stroke	24. Fever
	10. Malignancy	25. Elevated heart rate
	11. Critical illness*	26. Leukocytosis
	12. D-dimer	27. Low Barthel index score
	13. Autoimmune disease	28. Elevated C-reactive protein
	14. Obesity	29. Fibrinogen levels
	15. Hormone use	29. Fibrinogen levels
Panel input	1. Recent surgery <30 d before admission
	2. Recent long bone fractures
	3. Recent air travel
Bleeding
Included studies in the systematic review	1. Age ≥65 y	10. CVC use
	2. Sex	11. Active gastroduodenal ulcers in past 3 mo
	3. Renal failure	12. Hepatic disease
	4. Malignancy	13. Antithrombotic medication use†
	5. Critical illness	14. Rehospitalization†
	6. Autoimmune disease	15. Blood dyscrasias
	7. Obesity	16. Recent bleeding
	8. Hormone use	17. Low hemoglobin
	9. Thrombocytopenia	17. Low hemoglobin
Panel input	None

Immobility, acute paresis, and critical illness are risk factors that were assessed, both at admission and during the hospital stay.

Antithrombotic medication use and rehospitalization are risk factors that were assessed after admission.