Table 1. Laboratory data of the patient... | American Society of Hematology

Table 1.

Laboratory data of the patient

	Normal ranges	Baseline (age, 3 mo)	Baseline (age, 10 y)	During a bleeding episode	2 d after rTM (380 U/kg)
PLT, ×10³/µL	130-320	236	207	124	292
PT-INR	0.85-1.15	0.89	1.45	1.61	1.13
APTT, s	24.3-36.0	29.2	43.2	42.2	32.8
Fibrinogen, mg/dL	150-400	57	51	36	49
FDP, µg/mL	<5	77.7	65.7	198.2	6.3
D-dimer, µg/mL	<1.0	32.9	20.6	60.8	3.2
Protein C activity, %	46-156	41	96	106	104
TAT, ng/mL	<3.0	>60.0	>60.0	>60.0	6.2
PIC, µg/mL	<0.8	10.2	10.2	13.4	1.1
TM, ng/mL^*	2.3-3.7	<1.0	<1.0	<1.0	>201

	Normal ranges	Baseline (age, 3 mo)	Baseline (age, 10 y)	During a bleeding episode	2 d after rTM (380 U/kg)
PLT, ×10³/µL	130-320	236	207	124	292
PT-INR	0.85-1.15	0.89	1.45	1.61	1.13
APTT, s	24.3-36.0	29.2	43.2	42.2	32.8
Fibrinogen, mg/dL	150-400	57	51	36	49
FDP, µg/mL	<5	77.7	65.7	198.2	6.3
D-dimer, µg/mL	<1.0	32.9	20.6	60.8	3.2
Protein C activity, %	46-156	41	96	106	104
TAT, ng/mL	<3.0	>60.0	>60.0	>60.0	6.2
PIC, µg/mL	<0.8	10.2	10.2	13.4	1.1
TM, ng/mL^*	2.3-3.7	<1.0	<1.0	<1.0	>201

PLT, platelet count; PT-INR: prothrombin test–international normalized ratio.

The plasma TM concentration was measured by used a monoclonal antihuman TM antibody recognizing the thrombin-binding site.¹⁴