Correlation of mast cells with clinical characteristics
Factor . | No. . | Median . | Range . | P . |
---|---|---|---|---|
Total no. of mast cells | 56 | 59 | 3-142 | |
Sex | NS | |||
Male | 28 | 55.5 | 15-142 | |
Female | 28 | 60 | 3-118 | |
Age, y | NS | |||
<18 | 4 | 40.5 | 3-100 | |
≥18 | 52 | 59.5 | 13-142 | |
Donor type | NS | |||
Matched sibling/haploidentical | 20/1 | 59 | 13-142 | |
Matched unrelated donor | 4 | 66 | 26-100 | |
Single-unit umbilical cord blood | 8 | 51 | 23-126 | |
Double-unit umbilical cord blood | 23 | 60 | 3-118 | |
Diagnosis | NS | |||
AA | 1 | 26 | ||
ALL/AML/MDS/MPN | 39 | 60 | 3-142 | |
CML | 2 | 55 | 51-59 | |
NHL/HL | 8 | 53.5 | 25-78 | |
MM | 6 | 75.5 | 47-126 | |
Disease risk index | NS | |||
Low | 11 | 50 | 3-78 | |
Intermediate | 34 | 67.5 | 13-142 | |
High/very high | 10 | 58 | 32-91 | |
Nonmalignant | 1 | 26 | ||
Conditioning | <.01* | |||
MAC | 29 | 47 | 3-100 | |
RIC | 27 | 78 | 32-142 | |
GVHD prophylaxis | NS | |||
Cyclosporine A/methotrexate | 10 | 59 | 25-100 | |
Cyclosporine A/mycophenolate mofetil | 35 | 59 | 3-142 | |
Sirolimus/mycophenolate mofetil | 7 | 60 | 32-126 | |
Other | 4 | 50 | 23-91 | |
Karnofsky score | NS | |||
≤80 | 11 | 50 | 23-129 | |
>80 | 45 | 59 | 3-142 | |
HCT-specific comorbidity index | NS | |||
Low risk | 16 | 46.5 | 3-126 | |
Intermediate risk | 19 | 67 | 13-142 | |
High risk | 20 | 59.5 | 26-118 | |
Missing | 1 | — |
Factor . | No. . | Median . | Range . | P . |
---|---|---|---|---|
Total no. of mast cells | 56 | 59 | 3-142 | |
Sex | NS | |||
Male | 28 | 55.5 | 15-142 | |
Female | 28 | 60 | 3-118 | |
Age, y | NS | |||
<18 | 4 | 40.5 | 3-100 | |
≥18 | 52 | 59.5 | 13-142 | |
Donor type | NS | |||
Matched sibling/haploidentical | 20/1 | 59 | 13-142 | |
Matched unrelated donor | 4 | 66 | 26-100 | |
Single-unit umbilical cord blood | 8 | 51 | 23-126 | |
Double-unit umbilical cord blood | 23 | 60 | 3-118 | |
Diagnosis | NS | |||
AA | 1 | 26 | ||
ALL/AML/MDS/MPN | 39 | 60 | 3-142 | |
CML | 2 | 55 | 51-59 | |
NHL/HL | 8 | 53.5 | 25-78 | |
MM | 6 | 75.5 | 47-126 | |
Disease risk index | NS | |||
Low | 11 | 50 | 3-78 | |
Intermediate | 34 | 67.5 | 13-142 | |
High/very high | 10 | 58 | 32-91 | |
Nonmalignant | 1 | 26 | ||
Conditioning | <.01* | |||
MAC | 29 | 47 | 3-100 | |
RIC | 27 | 78 | 32-142 | |
GVHD prophylaxis | NS | |||
Cyclosporine A/methotrexate | 10 | 59 | 25-100 | |
Cyclosporine A/mycophenolate mofetil | 35 | 59 | 3-142 | |
Sirolimus/mycophenolate mofetil | 7 | 60 | 32-126 | |
Other | 4 | 50 | 23-91 | |
Karnofsky score | NS | |||
≤80 | 11 | 50 | 23-129 | |
>80 | 45 | 59 | 3-142 | |
HCT-specific comorbidity index | NS | |||
Low risk | 16 | 46.5 | 3-126 | |
Intermediate risk | 19 | 67 | 13-142 | |
High risk | 20 | 59.5 | 26-118 | |
Missing | 1 | — |
NS, not significant.
False discovery rate, 0.02.