Lymphomatoid papulosis: histologic subtypes and differential diagnosis
| LyP type . | Predominant phenotype . | Main differential diagnosis . |
|---|---|---|
| A (>80%) | CD4+, CD8− | C-ALCL |
| Tumor stage MF | ||
| Classic Hodgkin lymphoma | ||
| B (<5%) | CD4+, CD8− | Plaque stage MF |
| C (10%) | CD4+, CD8− | C-ALCL |
| Transformed MF (CD30+) | ||
| D (<5%) | CD4−, CD8+ | CD8+ aggressive epidermotropic T-cell lymphoma |
| E (<5%) | CD4−, CD8+ | Extranodal NK/T-cell lymphoma |
| With DUSP22-IRF4 rearrangement (<5%) | CD4−, CD8+ or CD4−, CD8− | Transformed MF |
| LyP type . | Predominant phenotype . | Main differential diagnosis . |
|---|---|---|
| A (>80%) | CD4+, CD8− | C-ALCL |
| Tumor stage MF | ||
| Classic Hodgkin lymphoma | ||
| B (<5%) | CD4+, CD8− | Plaque stage MF |
| C (10%) | CD4+, CD8− | C-ALCL |
| Transformed MF (CD30+) | ||
| D (<5%) | CD4−, CD8+ | CD8+ aggressive epidermotropic T-cell lymphoma |
| E (<5%) | CD4−, CD8+ | Extranodal NK/T-cell lymphoma |
| With DUSP22-IRF4 rearrangement (<5%) | CD4−, CD8+ or CD4−, CD8− | Transformed MF |