Expression levels of 11 proteins that returned to HTLV-1 state after achieving remission in ATL patients with P > .00001
| . | Protein name . | Elevation (up) or decrease (down) . | Protein function . | Protein coding gene . | UniProt . | P . |
|---|---|---|---|---|---|---|
| 1 | Soluble L-selectin | Down in remission | Leukocyte-endothelial cell adhesion | SELL | P14151 | 9.98E-8 |
| 2 | Cell adhesion molecule 1 | Down in remission | Cell adhesion | CADM1 | Q9BY67 | 1.26E-7 |
| 3 | TNFRSF8 | Down in remission | Regulation of cell growth, activated lymphoblast transformation | TNFRSF8 | P28908 | 1.62E-7 |
| 4 | LDL receptor related protein 8 | Down in remission | Cholesterol transport receptor | LRP8 | Q14114 | 6.03E-7 |
| 5 | Lymphocyte activation gene | Down in remission | Lymphocyte activation | LAG3 | P18627 | 6.23E-7 |
| 6 | Tissue inhibitor of metallopeptidase-1 | Down in remission | Promotion of erythroid progenitor stem cell proliferation | TIMP1 | P01033 | 9.17E-7 |
| 7 | Angiopoietin-2 | Down in remission | Vascular remodeling, proliferation | ANGPT2 | O15123 | 8.05E-06 |
| 8 | T-lymphocyte surface antigen Ly-9/CD229 | Down in remission | Innate immune response | LY9 | Q9HBG7 | 1.07E-6 |
| 9 | Deoxycytidine-triphosphatase 1 | Down in remission | DNA replication | DCTPP1 | Q9H773 | 1.14E-6 |
| 10 | T-cell cytokine receptor (WSX-1) TCCR | Down in remission | Induction of Th-1 type immune response | IL27RA | Q6UWB1 | 2.99E-6 |
| 11 | Ephrin A4 | Down in remission | Metastasis | EFNA4 | P52798 | 4.51E-6 |
| . | Protein name . | Elevation (up) or decrease (down) . | Protein function . | Protein coding gene . | UniProt . | P . |
|---|---|---|---|---|---|---|
| 1 | Soluble L-selectin | Down in remission | Leukocyte-endothelial cell adhesion | SELL | P14151 | 9.98E-8 |
| 2 | Cell adhesion molecule 1 | Down in remission | Cell adhesion | CADM1 | Q9BY67 | 1.26E-7 |
| 3 | TNFRSF8 | Down in remission | Regulation of cell growth, activated lymphoblast transformation | TNFRSF8 | P28908 | 1.62E-7 |
| 4 | LDL receptor related protein 8 | Down in remission | Cholesterol transport receptor | LRP8 | Q14114 | 6.03E-7 |
| 5 | Lymphocyte activation gene | Down in remission | Lymphocyte activation | LAG3 | P18627 | 6.23E-7 |
| 6 | Tissue inhibitor of metallopeptidase-1 | Down in remission | Promotion of erythroid progenitor stem cell proliferation | TIMP1 | P01033 | 9.17E-7 |
| 7 | Angiopoietin-2 | Down in remission | Vascular remodeling, proliferation | ANGPT2 | O15123 | 8.05E-06 |
| 8 | T-lymphocyte surface antigen Ly-9/CD229 | Down in remission | Innate immune response | LY9 | Q9HBG7 | 1.07E-6 |
| 9 | Deoxycytidine-triphosphatase 1 | Down in remission | DNA replication | DCTPP1 | Q9H773 | 1.14E-6 |
| 10 | T-cell cytokine receptor (WSX-1) TCCR | Down in remission | Induction of Th-1 type immune response | IL27RA | Q6UWB1 | 2.99E-6 |
| 11 | Ephrin A4 | Down in remission | Metastasis | EFNA4 | P52798 | 4.51E-6 |