Top 10 proteins with significantly different levels in HTLV-1 vs ATL
| . | Protein name . | Elevation (up) or decrease (down) . | Protein function . | Protein coding gene ID . | UniProt . | P . | AUC . |
|---|---|---|---|---|---|---|---|
| 1 | Coagulation factor Xa | Up in ATL | Blood coagulation | F10 | P00742 | 1.82E-16 | 0.99 |
| 2 | Coagulation factor X | Up in ATL | Blood coagulation | F10 | P00742 | 4.13E-16 | 0.99 |
| 3 | Cadherin-6 | Down in ATL | Cell adhesion | CDH6 | P55285 | 9.32E-14 | 0.93 |
| 4 | Insulin-like growth factor binding protein 4 | Up in ATL | IGF regulation | IGFBP4 | P22692 | 2.90E-12 | 0.91 |
| 5 | Lysozyme C | Up in ATL | Hydrolysis | LYZ | P61626 | 5.65E-12 | 0.89 |
| 6 | BDNF/NT-3 growth factor receptor | Down in ATL | Neuronal development and regulation | NTRK2 | Q16620 | 1.70E-11 | 0.88 |
| 7 | Granulins | Up in ATL | Cell growth regulation | GRN | P28799 | 2.73E-11 | 0.91 |
| 8 | RAS GTPase-activating protein 1 | Down in ATL | Cell proliferation and differentiation | RASA1 | P20936 | 2.77E-11 | 0.95 |
| 9 | Interleukin-18-binding protein | Up in ATL | Cell immunity induction | IL18BP | O95998 | 5.03E-11 | 0.93 |
| 10 | TNFR2 | Up in ATL | Apoptosis modulation and signaling | TNFRSF1B | P20333 | 6.82E-11 | 0.92 |
| . | Protein name . | Elevation (up) or decrease (down) . | Protein function . | Protein coding gene ID . | UniProt . | P . | AUC . |
|---|---|---|---|---|---|---|---|
| 1 | Coagulation factor Xa | Up in ATL | Blood coagulation | F10 | P00742 | 1.82E-16 | 0.99 |
| 2 | Coagulation factor X | Up in ATL | Blood coagulation | F10 | P00742 | 4.13E-16 | 0.99 |
| 3 | Cadherin-6 | Down in ATL | Cell adhesion | CDH6 | P55285 | 9.32E-14 | 0.93 |
| 4 | Insulin-like growth factor binding protein 4 | Up in ATL | IGF regulation | IGFBP4 | P22692 | 2.90E-12 | 0.91 |
| 5 | Lysozyme C | Up in ATL | Hydrolysis | LYZ | P61626 | 5.65E-12 | 0.89 |
| 6 | BDNF/NT-3 growth factor receptor | Down in ATL | Neuronal development and regulation | NTRK2 | Q16620 | 1.70E-11 | 0.88 |
| 7 | Granulins | Up in ATL | Cell growth regulation | GRN | P28799 | 2.73E-11 | 0.91 |
| 8 | RAS GTPase-activating protein 1 | Down in ATL | Cell proliferation and differentiation | RASA1 | P20936 | 2.77E-11 | 0.95 |
| 9 | Interleukin-18-binding protein | Up in ATL | Cell immunity induction | IL18BP | O95998 | 5.03E-11 | 0.93 |
| 10 | TNFR2 | Up in ATL | Apoptosis modulation and signaling | TNFRSF1B | P20333 | 6.82E-11 | 0.92 |