Landmark analysis of NRM including pre- and post-HCT measurements by age, biomarkers, and their interactions over time
| . | HR . | 95% CI . | P . |
|---|---|---|---|
| ST2 | |||
| Age 10 years or younger | 5.49 | 1.97-15.25 | .0011 |
| Age older than 10 years | 1.99 | 0.95-4.19 | .0693 |
| Age category | 1.98 | 0.82-4.78 | .1265 |
| Landmark | 1.00 | 0.99-1.01 | .8769 |
| TNFR1 | |||
| Age 10 years or younger | 2.49 | 0.89-6.99 | .0837 |
| Age older than 10 years | 1.33 | 0.61-2.90 | .4782 |
| Age category | 1.75 | 0.77-3.96 | .1798 |
| Landmark | 1.00 | 0.99-1.01 | .7764 |
| REG3α | |||
| Age 10 years or younger | 1.44 | 0.50-4.10 | .4963 |
| Age older than 10 years | 1.90 | 0.85-4.22 | .1157 |
| Age category | 1.12 | 0.39-3.23 | .8396 |
| Landmark | 0.99 | 0.98-1.00 | .1856 |
| IL-6 | |||
| Age 10 years or younger | 1.28 | 0.45-3.69 | .6434 |
| Age older than 10 years | 1.27 | 0.60-2.69 | .5274 |
| Age category | 1.38 | 0.62-3.03 | .4281 |
| Landmark | 0.99 | 0.97-1.00 | .0824 |
| . | HR . | 95% CI . | P . |
|---|---|---|---|
| ST2 | |||
| Age 10 years or younger | 5.49 | 1.97-15.25 | .0011 |
| Age older than 10 years | 1.99 | 0.95-4.19 | .0693 |
| Age category | 1.98 | 0.82-4.78 | .1265 |
| Landmark | 1.00 | 0.99-1.01 | .8769 |
| TNFR1 | |||
| Age 10 years or younger | 2.49 | 0.89-6.99 | .0837 |
| Age older than 10 years | 1.33 | 0.61-2.90 | .4782 |
| Age category | 1.75 | 0.77-3.96 | .1798 |
| Landmark | 1.00 | 0.99-1.01 | .7764 |
| REG3α | |||
| Age 10 years or younger | 1.44 | 0.50-4.10 | .4963 |
| Age older than 10 years | 1.90 | 0.85-4.22 | .1157 |
| Age category | 1.12 | 0.39-3.23 | .8396 |
| Landmark | 0.99 | 0.98-1.00 | .1856 |
| IL-6 | |||
| Age 10 years or younger | 1.28 | 0.45-3.69 | .6434 |
| Age older than 10 years | 1.27 | 0.60-2.69 | .5274 |
| Age category | 1.38 | 0.62-3.03 | .4281 |
| Landmark | 0.99 | 0.97-1.00 | .0824 |