Outcomes prioritized by the ASH Guideline Panel on Cerebrovascular Disease
| PICO question(s) . | Critical outcomes for decision-making . |
|---|---|
| 1, 2, and 3 | Stroke |
| 4 | Stroke recurrence |
| 5 | TIA |
| Stroke recurrence | |
| Acute chest syndrome | |
| Acute pain episode | |
| Total adverse events | |
| 6 | Stroke recurrence |
| SCI | |
| Mortality | |
| Postoperative complications including postoperative subdural hygroma; seizure; cerebral edema; subarachnoid and interventricular hemorrhage | |
| 7 | Improved functional outcome after stroke |
| Mortality | |
| Intracranial and other major hemorrhage | |
| 8 | Intelligence quotient/cognitive impairment, intelligence developmental delay, school performance |
| 9 | Cognitive impairment and school and work performance |
| 10 | SCI |
| Developmental delay, school and work performance, and cognitive impairment |
| PICO question(s) . | Critical outcomes for decision-making . |
|---|---|
| 1, 2, and 3 | Stroke |
| 4 | Stroke recurrence |
| 5 | TIA |
| Stroke recurrence | |
| Acute chest syndrome | |
| Acute pain episode | |
| Total adverse events | |
| 6 | Stroke recurrence |
| SCI | |
| Mortality | |
| Postoperative complications including postoperative subdural hygroma; seizure; cerebral edema; subarachnoid and interventricular hemorrhage | |
| 7 | Improved functional outcome after stroke |
| Mortality | |
| Intracranial and other major hemorrhage | |
| 8 | Intelligence quotient/cognitive impairment, intelligence developmental delay, school performance |
| 9 | Cognitive impairment and school and work performance |
| 10 | SCI |
| Developmental delay, school and work performance, and cognitive impairment |