Characteristics of patients with cHL undergoing haplo-SCT
| Characteristics . | All patients . | No-CPI . | CPI . | P . |
|---|---|---|---|---|
| n (%) | 59 (100) | 30 (51) | 29 (49) | |
| Median age (range), y | 30 (19-64) | 31 (19-64) | 30 (21-61) | .896 |
| Previous auto-SCT, n (%) | 49 (83) | 27 (90) | 22 (76) | .181 |
| Previous lines of therapy (range) | 5 (2-11) | 4 (2-11) | 6 (3-9) | <.001 |
| Disease status at haplo, n (%) | ||||
| CR | 40 (68) | 22 (73) | 18 (62) | .355 |
| PR | 14 (24) | 5 (17) | 9 (31) | |
| SD/PD | 5 (8) | 3 (10) | 2 (7) | |
| CMV serostatus, n (%) | ||||
| Recipient − | 20 (34) | 10 (33) | 10 (36) | .849 |
| Recipient + | 39 (66) | 20 (67) | 19 (64) | |
| Stem cell source, n (%) | ||||
| BM | 17 (29) | 7 (23) | 10 (36) | .345 |
| PBSC | 42 (71) | 23 (77) | 19 (64) | |
| Conditioning regimen, n (%) | ||||
| Nonmyeloablative | 45 (76) | 24 (80) | 21 (72) | .495 |
| Reduced toxicity | 14 (24) | 6 (20) | 8 (28) | |
| HCT-CI, n (%) | ||||
| 0-2 | 31 (52) | 14 (47) | 17 (59) | .358 |
| 3-5 | 28 (48) | 16 (53) | 12 (41) |
| Characteristics . | All patients . | No-CPI . | CPI . | P . |
|---|---|---|---|---|
| n (%) | 59 (100) | 30 (51) | 29 (49) | |
| Median age (range), y | 30 (19-64) | 31 (19-64) | 30 (21-61) | .896 |
| Previous auto-SCT, n (%) | 49 (83) | 27 (90) | 22 (76) | .181 |
| Previous lines of therapy (range) | 5 (2-11) | 4 (2-11) | 6 (3-9) | <.001 |
| Disease status at haplo, n (%) | ||||
| CR | 40 (68) | 22 (73) | 18 (62) | .355 |
| PR | 14 (24) | 5 (17) | 9 (31) | |
| SD/PD | 5 (8) | 3 (10) | 2 (7) | |
| CMV serostatus, n (%) | ||||
| Recipient − | 20 (34) | 10 (33) | 10 (36) | .849 |
| Recipient + | 39 (66) | 20 (67) | 19 (64) | |
| Stem cell source, n (%) | ||||
| BM | 17 (29) | 7 (23) | 10 (36) | .345 |
| PBSC | 42 (71) | 23 (77) | 19 (64) | |
| Conditioning regimen, n (%) | ||||
| Nonmyeloablative | 45 (76) | 24 (80) | 21 (72) | .495 |
| Reduced toxicity | 14 (24) | 6 (20) | 8 (28) | |
| HCT-CI, n (%) | ||||
| 0-2 | 31 (52) | 14 (47) | 17 (59) | .358 |
| 3-5 | 28 (48) | 16 (53) | 12 (41) |
The P value shown in bold represents <.05.
auto-SCT, autologous stem cell transplant; CMV, cytomegalovirus; CR, complete remission; PD, progressive disease; PR, partial remission; SD, stable disease.