Classification of histiocytoses
Histiocytosis group . | Diseases . |
---|---|
L Group | LCH |
Indeterminate-cell histiocytosis (ICH) | |
Erdheim-Chester Disease (ECD) | |
Mixed LCH/ECD | |
C Group | Cutaneous non-LCH |
Xanthomatous granuloma (XG) family: JXG, AXG, SRH, BCH, GEH, PNH | |
Non-XG family: cutaneous RDD, NXG, other | |
Cutaneous non-LCH with a major systemic component | |
XG family: XD | |
Non-XG family: MRH | |
R Group | Familial RDD |
Sporadic RDD | |
Classical RDD | |
Extranodal RDD | |
RDD with neoplasia or immune disease | |
Unclassified | |
M Group | Primary Malignant Histiocytoses |
Secondary Malignant Histiocytoses | |
H Group | Primary HLH: Monogenic inherited conditions leading to HLH |
Secondary HLH (non-Mendelian HLH) | |
HLH of unknown/uncertain origin |
Histiocytosis group . | Diseases . |
---|---|
L Group | LCH |
Indeterminate-cell histiocytosis (ICH) | |
Erdheim-Chester Disease (ECD) | |
Mixed LCH/ECD | |
C Group | Cutaneous non-LCH |
Xanthomatous granuloma (XG) family: JXG, AXG, SRH, BCH, GEH, PNH | |
Non-XG family: cutaneous RDD, NXG, other | |
Cutaneous non-LCH with a major systemic component | |
XG family: XD | |
Non-XG family: MRH | |
R Group | Familial RDD |
Sporadic RDD | |
Classical RDD | |
Extranodal RDD | |
RDD with neoplasia or immune disease | |
Unclassified | |
M Group | Primary Malignant Histiocytoses |
Secondary Malignant Histiocytoses | |
H Group | Primary HLH: Monogenic inherited conditions leading to HLH |
Secondary HLH (non-Mendelian HLH) | |
HLH of unknown/uncertain origin |
Adapted from Emile et al.21
AXG, adult xanthogranuloma; BCH, benign cephalic histiocytosis; GEH, generalized eruptive histiocytosis; JXG, juvenile xanthogranuloma; MRH, multicentric reticulohistiocytosis; NXG, necrobiotic xanthogranuloma; PNH, progressive nodular histiocytosis; RDD, Rosai-Dorfman Disease; SRH, solitary reticulohistiocytoma; XD, xanthoma disseminatum.