Table 3.

Univariable and multivariable analyses for OS

LabelModalityUnivariableMultivariable
HR95% CIPHR95% CIP
IPI 3-5 2.9 1.3 to 6.4 .0063    
TMTV >220 3.3 1.8 to 6.2 <.0001 3.1 1.6-5.7 .0005 
Treatment arm Lenalidomide 1.0 0.6 to 1.7 .90 1.2 0.7-2.0 .5 
NCCN-IPI score High-intermediate 3.3 1.3 to 8.3 .0097    
High 2.3 1.1 to 4.9 .0359    
ECOG PS ≥2 2.5 1.4 to 4.4 .0011 2.2 1.3-4.0 .0066 
Ann Arbor stage III-IV 2.9 0.7 to 12.0 .14    
LDH level Elevated 1.3 0.8 to 2.3 .31    
β2 microglobulin ≥3 mg/L 1.3 0.7 to 2.3 .45    
Albumin >35 g/L 0.5 0.3 to 0.9 .01    
Time to treatment (days)  1.0 0.99 to 1.0 .61    
LabelModalityUnivariableMultivariable
HR95% CIPHR95% CIP
IPI 3-5 2.9 1.3 to 6.4 .0063    
TMTV >220 3.3 1.8 to 6.2 <.0001 3.1 1.6-5.7 .0005 
Treatment arm Lenalidomide 1.0 0.6 to 1.7 .90 1.2 0.7-2.0 .5 
NCCN-IPI score High-intermediate 3.3 1.3 to 8.3 .0097    
High 2.3 1.1 to 4.9 .0359    
ECOG PS ≥2 2.5 1.4 to 4.4 .0011 2.2 1.3-4.0 .0066 
Ann Arbor stage III-IV 2.9 0.7 to 12.0 .14    
LDH level Elevated 1.3 0.8 to 2.3 .31    
β2 microglobulin ≥3 mg/L 1.3 0.7 to 2.3 .45    
Albumin >35 g/L 0.5 0.3 to 0.9 .01    
Time to treatment (days)  1.0 0.99 to 1.0 .61    
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