Posttransplant characteristics of patients undergoing first myeloablative HCT for AML at age 15-39 years between 2000-2014 who survived disease free for 12+ months (reported to the CIBMTR)
Variable . | All patients . | TBI . | Chemotherapy only . | |||
---|---|---|---|---|---|---|
No. . | % . | No. . | % . | No. . | % . | |
No. of patients | 826 | 390 | 436 | |||
aGVHD grade | ||||||
0 | 354 | 43 | 138 | 35 | 216 | 50 |
1 | 163 | 20 | 82 | 21 | 81 | 19 |
2 | 223 | 27 | 127 | 33 | 96 | 22 |
3 | 68 | 8 | 33 | 8 | 35 | 8 |
4 | 10 | 1 | 5 | 1 | 5 | 1 |
Maximum grade of cGVHD | ||||||
None | 371 | 45 | 178 | 46 | 193 | 44 |
Limited | 87 | 11 | 35 | 9 | 52 | 12 |
Extensive | 367 | 44 | 177 | 45 | 190 | 44 |
Reported cause of death | ||||||
Total deaths | 177 | 21 | 92 | 24 | 85 | 19 |
Primary disease | 68 | 8 | 33 | 8 | 35 | 8 |
GVHD | 28 | 3 | 18 | 5 | 10 | 2 |
Infection | 22 | 3 | 12 | 3 | 10 | 2 |
IPn/ARDS | 5 | <1 | 3 | <1 | 2 | <1 |
Organ failure | 19 | 2 | 8 | 2 | 11 | 3 |
SN | 1 | <1 | 0 | 1 | <1 | |
Other cause | 21 | 3 | 10 | 3 | 11 | 3 |
Variable . | All patients . | TBI . | Chemotherapy only . | |||
---|---|---|---|---|---|---|
No. . | % . | No. . | % . | No. . | % . | |
No. of patients | 826 | 390 | 436 | |||
aGVHD grade | ||||||
0 | 354 | 43 | 138 | 35 | 216 | 50 |
1 | 163 | 20 | 82 | 21 | 81 | 19 |
2 | 223 | 27 | 127 | 33 | 96 | 22 |
3 | 68 | 8 | 33 | 8 | 35 | 8 |
4 | 10 | 1 | 5 | 1 | 5 | 1 |
Maximum grade of cGVHD | ||||||
None | 371 | 45 | 178 | 46 | 193 | 44 |
Limited | 87 | 11 | 35 | 9 | 52 | 12 |
Extensive | 367 | 44 | 177 | 45 | 190 | 44 |
Reported cause of death | ||||||
Total deaths | 177 | 21 | 92 | 24 | 85 | 19 |
Primary disease | 68 | 8 | 33 | 8 | 35 | 8 |
GVHD | 28 | 3 | 18 | 5 | 10 | 2 |
Infection | 22 | 3 | 12 | 3 | 10 | 2 |
IPn/ARDS | 5 | <1 | 3 | <1 | 2 | <1 |
Organ failure | 19 | 2 | 8 | 2 | 11 | 3 |
SN | 1 | <1 | 0 | 1 | <1 | |
Other cause | 21 | 3 | 10 | 3 | 11 | 3 |
ARDS, acute respiratory distress syndrome; IPn, interstitial pneumonitis.