Characteristics of the 14 PCNSL patients with preexisting disorders
| Type of preexisting disorder . | Patients, n . | Histology . | Event . |
|---|---|---|---|
| Immunodeficiency | |||
| HIV infection | 2 | Burkitt lymphoma/DLBCL | No/dead: TRM (sepsis) |
| St. p. heart transplantation | 1 | DLBCL | Dead: TRM (graft failure) |
| St. p. kidney transplantation | 1 | DLBCL | No |
| St. p. liver transplantation | 1 | DLBCL | No |
| SLE | 1 | DLBCL | Dead (cause unknown) |
| CLIPPERS | 1 | DLBCL | No |
| Colitis ulcerosa | 1 | DLBCL | Dead: TRM (details NA) |
| PID n.f.s. | 2 | DLBCL/DLBCL | No/dead of disease |
| CVID | 1 | ALCL | Dead: TRM (pneumonia) |
| Other disorders | |||
| B-cell precursor LBL | 1 | DLBCL | No |
| JMML | 1 | DLBCL | Relapse |
| Factor VIII deficiency | 1 | ALCL | No |
| Type of preexisting disorder . | Patients, n . | Histology . | Event . |
|---|---|---|---|
| Immunodeficiency | |||
| HIV infection | 2 | Burkitt lymphoma/DLBCL | No/dead: TRM (sepsis) |
| St. p. heart transplantation | 1 | DLBCL | Dead: TRM (graft failure) |
| St. p. kidney transplantation | 1 | DLBCL | No |
| St. p. liver transplantation | 1 | DLBCL | No |
| SLE | 1 | DLBCL | Dead (cause unknown) |
| CLIPPERS | 1 | DLBCL | No |
| Colitis ulcerosa | 1 | DLBCL | Dead: TRM (details NA) |
| PID n.f.s. | 2 | DLBCL/DLBCL | No/dead of disease |
| CVID | 1 | ALCL | Dead: TRM (pneumonia) |
| Other disorders | |||
| B-cell precursor LBL | 1 | DLBCL | No |
| JMML | 1 | DLBCL | Relapse |
| Factor VIII deficiency | 1 | ALCL | No |
CLIPPERS, chronic lymphocytic inflammation with pontine perivascular enhancement responsive to steroids; CVID, common variable immunodeficiency; JMML, juvenile myelomonocytic leukemia; NA, not available; PID n.f.s., primary immunodeficiency not further specified; SLE, systemic lupus erythematosus; St. p., status post; TRM, treatment-related mortality.