Baseline characteristics of sickle cell disease patients in California, 1991 to 2014
| Variables . | All . | Bleeding . | No bleeding . | P . | |||
|---|---|---|---|---|---|---|---|
| N . | % . | n . | % . | n . | % . | ||
| All | 6423 | 100.0 | 1345 | 100.0 | 5078 | 100.0 | |
| Sex | |||||||
| Male | 3041 | 47.3 | 537 | 39.9 | 2504 | 49.3 | <.0001 |
| Female | 3382 | 52.7 | 808 | 60.1 | 2574 | 50.7 | <.0001 |
| Race/ethnicity | |||||||
| African American | 5767 | 89.8 | 1241 | 92.3 | 4526 | 89.1 | .0007 |
| Non–African American | 656 | 10.2 | 104 | 7.7 | 552 | 10.9 | .0007 |
| Hospitalization frequency* | |||||||
| Less frequent | 3639 | 56.7 | 491 | 36.5 | 3148 | 62.0 | <.0001 |
| Frequent | 2784 | 43.3 | 854 | 63.5 | 1930 | 38.0 | <.0001 |
| SCD complications before bleeding | |||||||
| Incident VTE or UE DVT | 695 | 10.8 | 193 | 14.3 | 502 | 9.9 | <.0001 |
| Pneumonia/ACS | 3633 | 56.6 | 731 | 54.3 | 2902 | 57.1 | 0.0656 |
| ACS* | 1639 | 25.5 | 271 | 20.1 | 1368 | 26.9 | <.0001 |
| ONFH | 1256 | 19.6 | 292 | 21.7 | 964 | 19.0 | 0.025 |
| Ischemic stroke | 228 | 3.5 | 61 | 4.5 | 167 | 3.3 | 0.028 |
| Renal failure | 480 | 7.5 | 150 | 11.2 | 330 | 6.5 | <.0001 |
| Liver failure | 517 | 8.0 | 164 | 12.2 | 353 | 7.0 | <.0001 |
| Deceased (as of 31 December 2013) | 1096 | 17.1 | 412 | 30.6 | 684 | 13.5 | <.0001 |
| Variables . | All . | Bleeding . | No bleeding . | P . | |||
|---|---|---|---|---|---|---|---|
| N . | % . | n . | % . | n . | % . | ||
| All | 6423 | 100.0 | 1345 | 100.0 | 5078 | 100.0 | |
| Sex | |||||||
| Male | 3041 | 47.3 | 537 | 39.9 | 2504 | 49.3 | <.0001 |
| Female | 3382 | 52.7 | 808 | 60.1 | 2574 | 50.7 | <.0001 |
| Race/ethnicity | |||||||
| African American | 5767 | 89.8 | 1241 | 92.3 | 4526 | 89.1 | .0007 |
| Non–African American | 656 | 10.2 | 104 | 7.7 | 552 | 10.9 | .0007 |
| Hospitalization frequency* | |||||||
| Less frequent | 3639 | 56.7 | 491 | 36.5 | 3148 | 62.0 | <.0001 |
| Frequent | 2784 | 43.3 | 854 | 63.5 | 1930 | 38.0 | <.0001 |
| SCD complications before bleeding | |||||||
| Incident VTE or UE DVT | 695 | 10.8 | 193 | 14.3 | 502 | 9.9 | <.0001 |
| Pneumonia/ACS | 3633 | 56.6 | 731 | 54.3 | 2902 | 57.1 | 0.0656 |
| ACS* | 1639 | 25.5 | 271 | 20.1 | 1368 | 26.9 | <.0001 |
| ONFH | 1256 | 19.6 | 292 | 21.7 | 964 | 19.0 | 0.025 |
| Ischemic stroke | 228 | 3.5 | 61 | 4.5 | 167 | 3.3 | 0.028 |
| Renal failure | 480 | 7.5 | 150 | 11.2 | 330 | 6.5 | <.0001 |
| Liver failure | 517 | 8.0 | 164 | 12.2 | 353 | 7.0 | <.0001 |
| Deceased (as of 31 December 2013) | 1096 | 17.1 | 412 | 30.6 | 684 | 13.5 | <.0001 |
DVT, deep vein thrombosis.
Hospitalization frequency: patients with SCD with an average of ≥3 visits per year (inpatient or ED) were defined as frequent; patients with an average of <3 visits per year were defined as less frequent. #ACS code available from 2003 onward.