Characteristics of B-cell lymphomas in patients with APDS
| Type of B-cell lymphoma . | EBV status (n) . | Total (APDS1/APDS2) n of patients . | M/F sex . | Median (range) age at lymphoma diagnosis, y* . | Lymphoma-associated death . | Reference . |
|---|---|---|---|---|---|---|
| Marginal zone lymphoma | NR | 5 (4/1) | 0/5 | 15 (13-18) | NR | 9,15,35,63 |
| Mucosa-associated lymphoid tissue lymphoma | EBV− (3) | 5 (4/1) | 4/1 | 21 (11-32) | NR | 15,19-21 |
| NR (2) | ||||||
| Hodgkin lymphoma | EBV+ (5) | 14 (9/5) | 4/8† | 15 (2.5-27) | 2 | 10,12,14,15,19,20,54,62,64 |
| NR (9) | ||||||
| Diffuse large-cell lymphoma | EBV+ (8) | 18 (13/5) | 3/14† | 22 (6-63) | 5 | 10,14,15,19,20,35,52,54,63,65 |
| EBV− (4) | ||||||
| NR (6) | ||||||
| Non-Hodgkin lymphoma (not otherwise specified) | EBV+ (2) | 5 (4/1) | 3/2 | 16 (8-20) | 1 | 19,20,66 |
| EBV− (1) | ||||||
| NR (2) | ||||||
| Posttransplantation lymphoproliferative disorder-like disease | EBV+ (3) | 3 (3/0) | 1/2 | 21 (8-59) | NR | 19 |
| Type of B-cell lymphoma . | EBV status (n) . | Total (APDS1/APDS2) n of patients . | M/F sex . | Median (range) age at lymphoma diagnosis, y* . | Lymphoma-associated death . | Reference . |
|---|---|---|---|---|---|---|
| Marginal zone lymphoma | NR | 5 (4/1) | 0/5 | 15 (13-18) | NR | 9,15,35,63 |
| Mucosa-associated lymphoid tissue lymphoma | EBV− (3) | 5 (4/1) | 4/1 | 21 (11-32) | NR | 15,19-21 |
| NR (2) | ||||||
| Hodgkin lymphoma | EBV+ (5) | 14 (9/5) | 4/8† | 15 (2.5-27) | 2 | 10,12,14,15,19,20,54,62,64 |
| NR (9) | ||||||
| Diffuse large-cell lymphoma | EBV+ (8) | 18 (13/5) | 3/14† | 22 (6-63) | 5 | 10,14,15,19,20,35,52,54,63,65 |
| EBV− (4) | ||||||
| NR (6) | ||||||
| Non-Hodgkin lymphoma (not otherwise specified) | EBV+ (2) | 5 (4/1) | 3/2 | 16 (8-20) | 1 | 19,20,66 |
| EBV− (1) | ||||||
| NR (2) | ||||||
| Posttransplantation lymphoproliferative disorder-like disease | EBV+ (3) | 3 (3/0) | 1/2 | 21 (8-59) | NR | 19 |