Table 5.

Genetics and clinical phenotypes

Gene identified, n (%)No gene identified, n (%)
United States, N = 234   
 Infections only, n = 91 23 (25) 68 (75) 
 Complications,* n = 143 50 (35) 93 (65) 
Sweden, N =113 with data   
 Infections only, n = 40 11 (27.5) 29 (72.5) 
 Complications,* n = 73 27 (36.9) 46 (63) 
Iran, N = 188 with data   
 Infections only, n = 80 43 (53.7) 37 (46.2) 
 Complications,* n = 108 62 (57) 46 (42.5) 
Gene identified, n (%)No gene identified, n (%)
United States, N = 234   
 Infections only, n = 91 23 (25) 68 (75) 
 Complications,* n = 143 50 (35) 93 (65) 
Sweden, N =113 with data   
 Infections only, n = 40 11 (27.5) 29 (72.5) 
 Complications,* n = 73 27 (36.9) 46 (63) 
Iran, N = 188 with data   
 Infections only, n = 80 43 (53.7) 37 (46.2) 
 Complications,* n = 108 62 (57) 46 (42.5) 
*

CVID complications include lymphocytic and or granulomatous infiltrations, lymphadenopathy/splenomegaly, autoimmunity, and noninfectious enteropathy.

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