Five-year probabilities of event-free and overall survival by age and donor type
| Donor type . | Event-free survival (95% CI), % . | Overall survival (95% CI), % . |
|---|---|---|
| Age, ≤6 y | ||
| HLA-matched relative | 88 (84-91) | 92 (89-95) |
| HLA-mismatched relative | 73 (59-86) | 75 (61-87) |
| HLA-matched unrelated | 89 (83-93) | 93 (88-96) |
| HLA-mismatched unrelated | 83 (73-91) | 89 (81-96) |
| Age, 7-15 y | ||
| HLA-matched relative | 80 (75-85) | 84 (79-88) |
| HLA-mismatched relative | 56 (39-73) | 62 (44-78) |
| HLA-matched unrelated | 89 (82-95) | 91 (83-97) |
| HLA-mismatched unrelated | 71 (54-85) | 79 (63-91) |
| Donor type . | Event-free survival (95% CI), % . | Overall survival (95% CI), % . |
|---|---|---|
| Age, ≤6 y | ||
| HLA-matched relative | 88 (84-91) | 92 (89-95) |
| HLA-mismatched relative | 73 (59-86) | 75 (61-87) |
| HLA-matched unrelated | 89 (83-93) | 93 (88-96) |
| HLA-mismatched unrelated | 83 (73-91) | 89 (81-96) |
| Age, 7-15 y | ||
| HLA-matched relative | 80 (75-85) | 84 (79-88) |
| HLA-mismatched relative | 56 (39-73) | 62 (44-78) |
| HLA-matched unrelated | 89 (82-95) | 91 (83-97) |
| HLA-mismatched unrelated | 71 (54-85) | 79 (63-91) |
Patients aged 16-25 years: N = 24 patients who received HLA-matched related donor transplantation with event-free survival of 58% (14 of 24) and overall survival of 63% (15 of 24). N = 4 patients received HLA-mismatched related donor transplantation and only 2 patients are alive. N = 4 patients received HLA-matched unrelated donor transplantation and all patients are alive. N = 1 patient received HLA-mismatched unrelated donor transplantation and is death.