Table 3.

Cox regression analysis of prognostic factors for survival after relapse

FactorRR 95% CI
Donor type  
 HLA-identical sibling  
 Volunteer unrelated  1.58  1.07-2.30  
Disease phase at SCT  
 1st CP  1  
 >1st CP  2.03  1.60-2.56 
Interval from Dx to SCT  
 <2 yr  1  
 ≥2 yr  1.40 1.11-1.76  
Interval from SCT to relapse  
 ≥1 yr  
 <1 yr  2.28  1.82-2.87  
Disease stage at relapse 
 CYT or HCP  1  
 HAP  3.08  2.41-3.88 
FactorRR 95% CI
Donor type  
 HLA-identical sibling  
 Volunteer unrelated  1.58  1.07-2.30  
Disease phase at SCT  
 1st CP  1  
 >1st CP  2.03  1.60-2.56 
Interval from Dx to SCT  
 <2 yr  1  
 ≥2 yr  1.40 1.11-1.76  
Interval from SCT to relapse  
 ≥1 yr  
 <1 yr  2.28  1.82-2.87  
Disease stage at relapse 
 CYT or HCP  1  
 HAP  3.08  2.41-3.88 

RR indicates risk ratio; CI, confidence interval; Dx, diagnosis; SCT, stem cell transplantation; CP, chronic phase; CYT, cytogenetic relapse; HCP, hematologic relapse in CP; HAP, hematologic relapse in advanced phase (ie, accelerated phase or blastic phase).

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