HLA-B allele frequencies in sickle cell anemia patients with and without stroke
| Allele . | Stroke (2n = 44) . | Control (2n = 62) . | G* . | Odds ratio . | 95% confidence interval . | P . | ||
|---|---|---|---|---|---|---|---|---|
| Number . | % . | Number . | % . | |||||
| 0702 | 3 | 7 | 8 | 13 | 1.0 | |||
| 0705† | 1 | 2 | 1 | 2 | ||||
| 0801† | 1 | 2 | 0 | 0 | ||||
| 1302† | 0 | 0 | 1 | 2 | ||||
| 1402† | 0 | 0 | 2 | 3 | ||||
| 1501† | 1 | 2 | 0 | 0 | ||||
| 1503 | 5 | 11 | 3 | 5 | 1.4 | |||
| 1510† | 0 | 0 | 4 | 6 | ||||
| 1516† | 1 | 2 | 2 | 3 | ||||
| 1520† | 0 | 0 | 1 | 2 | ||||
| 1801† | 0 | 0 | 1 | 2 | ||||
| 2703† | 1 | 2 | 0 | 0 | ||||
| 3501 | 7 | 16 | 6 | 10 | 0.8 | |||
| 3505† | 1 | 2 | 0 | 0 | ||||
| 3507† | 1 | 2 | 0 | 0 | ||||
| 4001† | 0 | 0 | 1 | 2 | ||||
| 4101† | 0 | 0 | 1 | 2 | ||||
| 4202 | 4 | 9 | 2 | 3 | 1.5 | |||
| 4402† | 0 | 0 | 1 | 2 | ||||
| 4403† | 0 | 0 | 1 | 2 | ||||
| 4501 | 0 | 0 | 7 | 11 | 7.5 | 0.08 | 0.01-1.50 | .04 |
| 4901† | 0 | 0 | 1 | 2 | ||||
| 5001† | 2 | 5 | 2 | 3 | ||||
| 5101† | 2 | 5 | 1 | 2 | ||||
| 5201 | 1 | 2 | 4 | 6 | 1 | |||
| 5301 | 9 | 20 | 4 | 6 | 4.1 | 3.7 | 1.13-12.34 | .038 |
| 5501† | 0 | 0 | 1 | 2 | ||||
| 5701† | 0 | 0 | 1 | 2 | ||||
| 5703† | 1 | 2 | 2 | 3 | ||||
| 5801† | 1 | 2 | 0 | 0 | ||||
| 5802† | 2 | 5 | 2 | 3 | ||||
| 8101† | 0 | 0 | 2 | 3 | ||||
| “Combined” alleles | 15 | 34 | 28 | 45 | 0.8 | |||
| Total G‡ | 18.1 | .012 | ||||||
| Allele . | Stroke (2n = 44) . | Control (2n = 62) . | G* . | Odds ratio . | 95% confidence interval . | P . | ||
|---|---|---|---|---|---|---|---|---|
| Number . | % . | Number . | % . | |||||
| 0702 | 3 | 7 | 8 | 13 | 1.0 | |||
| 0705† | 1 | 2 | 1 | 2 | ||||
| 0801† | 1 | 2 | 0 | 0 | ||||
| 1302† | 0 | 0 | 1 | 2 | ||||
| 1402† | 0 | 0 | 2 | 3 | ||||
| 1501† | 1 | 2 | 0 | 0 | ||||
| 1503 | 5 | 11 | 3 | 5 | 1.4 | |||
| 1510† | 0 | 0 | 4 | 6 | ||||
| 1516† | 1 | 2 | 2 | 3 | ||||
| 1520† | 0 | 0 | 1 | 2 | ||||
| 1801† | 0 | 0 | 1 | 2 | ||||
| 2703† | 1 | 2 | 0 | 0 | ||||
| 3501 | 7 | 16 | 6 | 10 | 0.8 | |||
| 3505† | 1 | 2 | 0 | 0 | ||||
| 3507† | 1 | 2 | 0 | 0 | ||||
| 4001† | 0 | 0 | 1 | 2 | ||||
| 4101† | 0 | 0 | 1 | 2 | ||||
| 4202 | 4 | 9 | 2 | 3 | 1.5 | |||
| 4402† | 0 | 0 | 1 | 2 | ||||
| 4403† | 0 | 0 | 1 | 2 | ||||
| 4501 | 0 | 0 | 7 | 11 | 7.5 | 0.08 | 0.01-1.50 | .04 |
| 4901† | 0 | 0 | 1 | 2 | ||||
| 5001† | 2 | 5 | 2 | 3 | ||||
| 5101† | 2 | 5 | 1 | 2 | ||||
| 5201 | 1 | 2 | 4 | 6 | 1 | |||
| 5301 | 9 | 20 | 4 | 6 | 4.1 | 3.7 | 1.13-12.34 | .038 |
| 5501† | 0 | 0 | 1 | 2 | ||||
| 5701† | 0 | 0 | 1 | 2 | ||||
| 5703† | 1 | 2 | 2 | 3 | ||||
| 5801† | 1 | 2 | 0 | 0 | ||||
| 5802† | 2 | 5 | 2 | 3 | ||||
| 8101† | 0 | 0 | 2 | 3 | ||||
| “Combined” alleles | 15 | 34 | 28 | 45 | 0.8 | |||
| Total G‡ | 18.1 | .012 | ||||||