Table 2.

Effect of lymphocytotoxicity screening assay on platelet increments 1 hour after granulocyte transfusions

Transplant day of component transfusionComponent cell dose (×1011)*Absolute platelet increment (×103/μL)*CCI (×103/μL)*
Overall s-LCA negatives-LCA positive POverall s-LCA negative s-LCA positive POveralls-LCA negative s-LCA positive P
+2 4.1 (2.6-6.2)  4.0 (2.6-6.2)  4.2 (2.9-5.9)  0.73 14 (0-49)  11 (0-20)  15 (0-49)  0.99  6.5 (0-24.6) 5.5 (0-12.1)  6.8 (0-24.6)  0.77  
+4  3.3 (1.5-5.0) 3.3 (1.5-5.0)  3.1 (2.5-4.1)  0.68  12 (0-59) 8 (0-22)  18 (0-59)  0.20  7.6 (0-39.5) 5.2 (0-20.7)  11.6 (0-39.5)  0.32  
+6  2.7 (2.1-3.6) 2.7 (2.1-3.6)  2.6 (2.1-3.1)  0.74  8 (0-21) 10 (0-21)  5 (0-11)  0.21  6.8 (0-35.0) 6.3 (0-14.4)  7.8 (0-35.0)  0.33  
+8  2.4 (1.5-3.0) 2.2 (1.5-2.8)  2.5 (1.8-3.0)  0.36  8 (0-16) 7 (0-16)  10 (7-13)  0.24  6.8 (0-15.1) 6.0 (0-15.1)  7.8 (4.3-10.2)  0.30 
Transplant day of component transfusionComponent cell dose (×1011)*Absolute platelet increment (×103/μL)*CCI (×103/μL)*
Overall s-LCA negatives-LCA positive POverall s-LCA negative s-LCA positive POveralls-LCA negative s-LCA positive P
+2 4.1 (2.6-6.2)  4.0 (2.6-6.2)  4.2 (2.9-5.9)  0.73 14 (0-49)  11 (0-20)  15 (0-49)  0.99  6.5 (0-24.6) 5.5 (0-12.1)  6.8 (0-24.6)  0.77  
+4  3.3 (1.5-5.0) 3.3 (1.5-5.0)  3.1 (2.5-4.1)  0.68  12 (0-59) 8 (0-22)  18 (0-59)  0.20  7.6 (0-39.5) 5.2 (0-20.7)  11.6 (0-39.5)  0.32  
+6  2.7 (2.1-3.6) 2.7 (2.1-3.6)  2.6 (2.1-3.1)  0.74  8 (0-21) 10 (0-21)  5 (0-11)  0.21  6.8 (0-35.0) 6.3 (0-14.4)  7.8 (0-35.0)  0.33  
+8  2.4 (1.5-3.0) 2.2 (1.5-2.8)  2.5 (1.8-3.0)  0.36  8 (0-16) 7 (0-16)  10 (7-13)  0.24  6.8 (0-15.1) 6.0 (0-15.1)  7.8 (4.3-10.2)  0.30 
*

Mean (range).

t test.

Mann-Whitney U test.

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