Table 3.

Frequencies of relapse and treatment-related mortality according to disease and treatment characteristics

RelapseTreatment-related mortality rates
Low cell dose (%) High cell dose (%) Low cell dose (%) High cell dose (%)
Disease  
 Acute leukemia 16/35 (46)  16/38 (42)  5/35 (14)  1/38 (3)  
 CML 12/15 (80)  6/12 (55)  1/15 (7)  0/12 (0)  
Stage before transplantation  
 Early  22/38 (58)  9/27 (33) 4/38 (11)  1/27 (4)  
 Intermediate  5/8 (62) 6/16 (38)  0/8 (0)  0/16 (0)  
 Advanced  1/4 (25) 7/7 (100)  2/4 (50)  0/7 (0)  
WBC at diagnosis 
 ≤25 × 109/L  11/29 (38)  11/28 (39) 3/29 (10)  1/28 (4)  
 >25 × 109/L 17/21 (81)  11/22 (50)  3/21 (14)  0/22 (0) 
Conditioning  
 BuCY  12/18 (67)  8/17 (47) 2/18 (11)  0/17 (0)  
 CyTBI  16/32 (50) 14/33 (42)  4/32 (13)  1/33 (3) 
RelapseTreatment-related mortality rates
Low cell dose (%) High cell dose (%) Low cell dose (%) High cell dose (%)
Disease  
 Acute leukemia 16/35 (46)  16/38 (42)  5/35 (14)  1/38 (3)  
 CML 12/15 (80)  6/12 (55)  1/15 (7)  0/12 (0)  
Stage before transplantation  
 Early  22/38 (58)  9/27 (33) 4/38 (11)  1/27 (4)  
 Intermediate  5/8 (62) 6/16 (38)  0/8 (0)  0/16 (0)  
 Advanced  1/4 (25) 7/7 (100)  2/4 (50)  0/7 (0)  
WBC at diagnosis 
 ≤25 × 109/L  11/29 (38)  11/28 (39) 3/29 (10)  1/28 (4)  
 >25 × 109/L 17/21 (81)  11/22 (50)  3/21 (14)  0/22 (0) 
Conditioning  
 BuCY  12/18 (67)  8/17 (47) 2/18 (11)  0/17 (0)  
 CyTBI  16/32 (50) 14/33 (42)  4/32 (13)  1/33 (3) 
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