Frequencies of relapse and treatment-related mortality according to disease and treatment characteristics
. | Relapse . | Treatment-related mortality rates . | ||
---|---|---|---|---|
Low cell dose (%) . | High cell dose (%) . | Low cell dose (%) . | High cell dose (%) . | |
Disease | ||||
Acute leukemia | 16/35 (46) | 16/38 (42) | 5/35 (14) | 1/38 (3) |
CML | 12/15 (80) | 6/12 (55) | 1/15 (7) | 0/12 (0) |
Stage before transplantation | ||||
Early | 22/38 (58) | 9/27 (33) | 4/38 (11) | 1/27 (4) |
Intermediate | 5/8 (62) | 6/16 (38) | 0/8 (0) | 0/16 (0) |
Advanced | 1/4 (25) | 7/7 (100) | 2/4 (50) | 0/7 (0) |
WBC at diagnosis | ||||
≤25 × 109/L | 11/29 (38) | 11/28 (39) | 3/29 (10) | 1/28 (4) |
>25 × 109/L | 17/21 (81) | 11/22 (50) | 3/21 (14) | 0/22 (0) |
Conditioning | ||||
BuCY | 12/18 (67) | 8/17 (47) | 2/18 (11) | 0/17 (0) |
CyTBI | 16/32 (50) | 14/33 (42) | 4/32 (13) | 1/33 (3) |
. | Relapse . | Treatment-related mortality rates . | ||
---|---|---|---|---|
Low cell dose (%) . | High cell dose (%) . | Low cell dose (%) . | High cell dose (%) . | |
Disease | ||||
Acute leukemia | 16/35 (46) | 16/38 (42) | 5/35 (14) | 1/38 (3) |
CML | 12/15 (80) | 6/12 (55) | 1/15 (7) | 0/12 (0) |
Stage before transplantation | ||||
Early | 22/38 (58) | 9/27 (33) | 4/38 (11) | 1/27 (4) |
Intermediate | 5/8 (62) | 6/16 (38) | 0/8 (0) | 0/16 (0) |
Advanced | 1/4 (25) | 7/7 (100) | 2/4 (50) | 0/7 (0) |
WBC at diagnosis | ||||
≤25 × 109/L | 11/29 (38) | 11/28 (39) | 3/29 (10) | 1/28 (4) |
>25 × 109/L | 17/21 (81) | 11/22 (50) | 3/21 (14) | 0/22 (0) |
Conditioning | ||||
BuCY | 12/18 (67) | 8/17 (47) | 2/18 (11) | 0/17 (0) |
CyTBI | 16/32 (50) | 14/33 (42) | 4/32 (13) | 1/33 (3) |