Characteristics of all patients in study and according to risk group
| Characteristic . | All patients, n (%) (total n = 2178) . | Risk group, % of patients in each . | ||
|---|---|---|---|---|
| SRG (n = 636, 29.2%) . | MRG (n = 1299, 59.7%) . | HRG (n = 243, 11.1%) . | ||
| Male | 1261 (57.9) | 52.5 | 58.0 | 71.2 |
| Age, y | ||||
| <1 | 59 (2.7) | 0.9 | 3.2 | 4.9 |
| 1-5 | 1316 (60.4) | 62.9 | 63.7 | 36.2 |
| 6-9 | 417 (19.2) | 21.9 | 16.7 | 25.1 |
| ≥10 | 386 (17.7) | 14.3 | 16.4 | 33.8 |
| WBC count, ×109/L | ||||
| <10 | 1000 (45.9) | 94.3 | 28.3 | 13.2 |
| 10-50 | 693 (31.8) | 5.7 | 45.4 | 27.1 |
| ≥50 | 485 (22.3) | 0 | 26.2 | 59.7 |
| BFM-RF | ||||
| <0.8 | 688 (31.6) | 99.8 | 3.0 | 5.8 |
| ≥0.8 | 1490 (68.4) | 0.2 | 97.0 | 94.2 |
| CNS involvement | 54 (2.5) | 0 | 2.7 | 7.4 |
| Immunophenotype* | ||||
| Pro-B | 103 (4.9) | 3.0 | 4.9 | 9.6 |
| Common | 1364 (64.4) | 79.2 | 63.0 | 37.2 |
| Pre-B | 359 (17.0) | 17.8 | 18.3 | 8.4 |
| T cell | 284 (13.5) | 0 | 13.8 | 44.8 |
| Characteristic . | All patients, n (%) (total n = 2178) . | Risk group, % of patients in each . | ||
|---|---|---|---|---|
| SRG (n = 636, 29.2%) . | MRG (n = 1299, 59.7%) . | HRG (n = 243, 11.1%) . | ||
| Male | 1261 (57.9) | 52.5 | 58.0 | 71.2 |
| Age, y | ||||
| <1 | 59 (2.7) | 0.9 | 3.2 | 4.9 |
| 1-5 | 1316 (60.4) | 62.9 | 63.7 | 36.2 |
| 6-9 | 417 (19.2) | 21.9 | 16.7 | 25.1 |
| ≥10 | 386 (17.7) | 14.3 | 16.4 | 33.8 |
| WBC count, ×109/L | ||||
| <10 | 1000 (45.9) | 94.3 | 28.3 | 13.2 |
| 10-50 | 693 (31.8) | 5.7 | 45.4 | 27.1 |
| ≥50 | 485 (22.3) | 0 | 26.2 | 59.7 |
| BFM-RF | ||||
| <0.8 | 688 (31.6) | 99.8 | 3.0 | 5.8 |
| ≥0.8 | 1490 (68.4) | 0.2 | 97.0 | 94.2 |
| CNS involvement | 54 (2.5) | 0 | 2.7 | 7.4 |
| Immunophenotype* | ||||
| Pro-B | 103 (4.9) | 3.0 | 4.9 | 9.6 |
| Common | 1364 (64.4) | 79.2 | 63.0 | 37.2 |
| Pre-B | 359 (17.0) | 17.8 | 18.3 | 8.4 |
| T cell | 284 (13.5) | 0 | 13.8 | 44.8 |
WBC indicates white blood cell; BFM-RF, BFM risk factor (see text); and CNS, central nervous system.
In patients who underwent immunophenotypic analysis.