Immunoglobulin production by the mice and microscopic analysis of the kidneys
| Mice . | Serum monoclonal peak (g/L) . | Serum cryoglobulin . | Crystals in tumoral cells . | Crystalline organized subendothelial deposits . | Amorphous cryoglobulin thrombi . |
|---|---|---|---|---|---|
| 8A4 | |||||
| 1 | − | − | + | + | − |
| 2 | − | − | + | + | − |
| 3 | − | − | + | + | − |
| 4 | − | − | + | + | − |
| 5 | − | − | + | + | − |
| 8A4-NP1 | |||||
| 1 | 30 | + | − | − | + |
| 2 | 32 | + | − | − | + |
| 3 | 38 | + | − | − | + |
| 4 | 34 | + | − | − | + |
| Mice . | Serum monoclonal peak (g/L) . | Serum cryoglobulin . | Crystals in tumoral cells . | Crystalline organized subendothelial deposits . | Amorphous cryoglobulin thrombi . |
|---|---|---|---|---|---|
| 8A4 | |||||
| 1 | − | − | + | + | − |
| 2 | − | − | + | + | − |
| 3 | − | − | + | + | − |
| 4 | − | − | + | + | − |
| 5 | − | − | + | + | − |
| 8A4-NP1 | |||||
| 1 | 30 | + | − | − | + |
| 2 | 32 | + | − | − | + |
| 3 | 38 | + | − | − | + |
| 4 | 34 | + | − | − | + |
Summarized data in each set of mice (8A4, 8A4-NP1): concentrations of the monoclonal peak in serum and results of immunofluorescence and electron microscopy study of mice kidneys.