Proportional Hazards Regression Model for Mortality According to Either Donor or Recipient Disparity
Donor or Recipient Disparity3-150 . | No. of Pairs . | Hazard Ratio (95% confidence interval) . | P Value . |
---|---|---|---|
Allele match | 142 | 1.0 (—) | — |
Single class I | 55 | 1.2 (0.7-2.1) | .40 |
Multiple class I | 35 | 3.5 (2.1-5.9) | <.001 |
Single class II | 24 | 1.0 (0.5-2.1) | .89 |
Class I and class II | 37 | 3.3 (2.0-5.5) | <.001 |
Donor or Recipient Disparity3-150 . | No. of Pairs . | Hazard Ratio (95% confidence interval) . | P Value . |
---|---|---|---|
Allele match | 142 | 1.0 (—) | — |
Single class I | 55 | 1.2 (0.7-2.1) | .40 |
Multiple class I | 35 | 3.5 (2.1-5.9) | <.001 |
Single class II | 24 | 1.0 (0.5-2.1) | .89 |
Class I and class II | 37 | 3.3 (2.0-5.5) | <.001 |
Adjusted for stage of disease, body weight index, time interval from diagnosis to transplant, patient age at time of transplant, availability of fluconazole and ganciclovir, and patient CMV seropositivity.
Seven patients had multiple class II mismatches and 3 died.