Summary of BV8-CDR3-BJ2S3 Sequences and Their Associations With HLA-DRB15-1500401 Alleles and BV8 CD4 T-Cell Expansions
| Patient No. . | BV8-CDR3-J2S3 Motif5-150 . | DRB15-1500401 Allele . | BV8+ CD4 Expansion5-151 . |
|---|---|---|---|
| 1 | Yes (3/12)5-152 | Yes | No5-153 |
| 2 | Yes (15/24) | Yes | Yes |
| 3 | Yes (4/4-13/17) | Yes | Yes |
| 4 | ND | No | No |
| 5 | No (0/15) | No | No |
| 6 | No (0/11) | No | Yes |
| 7 | Yes (9/11) | Yes | Yes |
| 8 | No (0/9) | Yes | No |
| Patient No. . | BV8-CDR3-J2S3 Motif5-150 . | DRB15-1500401 Allele . | BV8+ CD4 Expansion5-151 . |
|---|---|---|---|
| 1 | Yes (3/12)5-152 | Yes | No5-153 |
| 2 | Yes (15/24) | Yes | Yes |
| 3 | Yes (4/4-13/17) | Yes | Yes |
| 4 | ND | No | No |
| 5 | No (0/15) | No | No |
| 6 | No (0/11) | No | Yes |
| 7 | Yes (9/11) | Yes | Yes |
| 8 | No (0/9) | Yes | No |
Abbreviation: nd, not determined.
Presence and frequency of the BV8-F/L-G-G-A/Q-G-J2S3 motif.
BV8 expansion in CD4+ T cells as defined in reference 4 (ie >14.6%) at the time of or before sequencing analysis.
One additional similar sequence.
No data on BV8 CD4 before the sequence analysis was available.