Summary of the available prospective studies evaluating the prevalence of bacterial contamination in whole blood–derived platelets, apheresis platelets, and red blood cell units.
| Blood Produce Type . | Reference . | Positives per Number of Units Tested . | Contamination Prevalence per 100,000 Units . |
|---|---|---|---|
| * 95% confidence intervals 25.6 to 39.1 | |||
| Abbreviations: A-plts, apheresis platelets; WB-plts, whole blood–derived platelets; RBCs, red blood cells; n, number of studies. | |||
| WB-plts | Morrow et al32 | 6 per 74,598 | 8 |
| WB-plts | Barrett et al33 | 1 per 4,272 | 23 |
| WB-plts | Yomtovian et al34 | 6 per 15,705 | 38 |
| WB-plts | Chiu et al35 | 10 per 21,503 | 46 |
| WB-plts | Blajchman et al36 | 16 per 31,610 | 51 |
| WB-plts | Leiby et al37 | 4 per 4,995 | 80 |
| WB-plts | Blajchman et al38 | 7 per 10,065 | 70 |
| A-plts | Morrow et al32 | 1 per 9,519 | 5 |
| A-plts | Blajchman et al31 | 14 per 6,055 | 230 |
| A-plts | Barrett et al33 | 5 per 17,928 | 28 |
| A-plts | Yomtovian et al34 | 0 per 2,476 | 0 |
| A-plts | Dzieczkowski et al39 | 1 per 5,197 | 19 |
| A-plts | Aubuchon et al40 | 1 per 2,678 | 37 |
| RBCs | Barrett et al33 | 1 per 31,385 | 3 |
| RBCs | Dzieczkowski et al39 | 1 per 7,080 | 0 |
| Overall | n = 15 | 89 per 274,379 | 32.4* |
| Blood Produce Type . | Reference . | Positives per Number of Units Tested . | Contamination Prevalence per 100,000 Units . |
|---|---|---|---|
| * 95% confidence intervals 25.6 to 39.1 | |||
| Abbreviations: A-plts, apheresis platelets; WB-plts, whole blood–derived platelets; RBCs, red blood cells; n, number of studies. | |||
| WB-plts | Morrow et al32 | 6 per 74,598 | 8 |
| WB-plts | Barrett et al33 | 1 per 4,272 | 23 |
| WB-plts | Yomtovian et al34 | 6 per 15,705 | 38 |
| WB-plts | Chiu et al35 | 10 per 21,503 | 46 |
| WB-plts | Blajchman et al36 | 16 per 31,610 | 51 |
| WB-plts | Leiby et al37 | 4 per 4,995 | 80 |
| WB-plts | Blajchman et al38 | 7 per 10,065 | 70 |
| A-plts | Morrow et al32 | 1 per 9,519 | 5 |
| A-plts | Blajchman et al31 | 14 per 6,055 | 230 |
| A-plts | Barrett et al33 | 5 per 17,928 | 28 |
| A-plts | Yomtovian et al34 | 0 per 2,476 | 0 |
| A-plts | Dzieczkowski et al39 | 1 per 5,197 | 19 |
| A-plts | Aubuchon et al40 | 1 per 2,678 | 37 |
| RBCs | Barrett et al33 | 1 per 31,385 | 3 |
| RBCs | Dzieczkowski et al39 | 1 per 7,080 | 0 |
| Overall | n = 15 | 89 per 274,379 | 32.4* |