Table 6.

Classification of patients having antiphospholipid (aPL) antibodies.

Abbreviations: aPL, antiphospholipid; CMV, cytomegalovirus; EBV, Epstein-Barr virus; HIV, human immunodeficiency virus; SLE, systemic lupus erythematosus. 

  • Autoimmune aPL syndrome

    • Primary

    • Secondary—associated with SLE

  • aPL antibodies stimulated by infection

    • No known association with thrombosis—e.g., syphilis, Lyme disease, EBV, CMV

    • Possible association with thrombosis—e.g., varicella, HIV, hepatitis C

  • Drug-induced aPL antibodies

  • aPL antibodies prevalent in the general population

 
Abbreviations: aPL, antiphospholipid; CMV, cytomegalovirus; EBV, Epstein-Barr virus; HIV, human immunodeficiency virus; SLE, systemic lupus erythematosus. 

  • Autoimmune aPL syndrome

    • Primary

    • Secondary—associated with SLE

  • aPL antibodies stimulated by infection

    • No known association with thrombosis—e.g., syphilis, Lyme disease, EBV, CMV

    • Possible association with thrombosis—e.g., varicella, HIV, hepatitis C

  • Drug-induced aPL antibodies

  • aPL antibodies prevalent in the general population

 
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