Comparison of the incidence and outcome of the retinoic acid syndrome (RAS).
| Study . | n . | Induction . | Incidence (%) . | Mortality (%) of Pts with RAS . | Mortality (%) of all treated Pts due to RAS . |
|---|---|---|---|---|---|
| ALSG27 | 87 | ATRA + steroids | 16 | 21 | 3 |
| No. Amer. Intergroup14 | 172 | ATRA | 26 | 5 | 1 |
| JALSG21 | 196 | ATRA ± chemo | 6 | 9 | 0.5 |
| APL 9315 | 413 | ATRA ± chemo | 15 | 8 | 1 |
| PETHEMA12 | 123 | ATRA + chemo | 6 | 17 | 0.8 |
| Study . | n . | Induction . | Incidence (%) . | Mortality (%) of Pts with RAS . | Mortality (%) of all treated Pts due to RAS . |
|---|---|---|---|---|---|
| ALSG27 | 87 | ATRA + steroids | 16 | 21 | 3 |
| No. Amer. Intergroup14 | 172 | ATRA | 26 | 5 | 1 |
| JALSG21 | 196 | ATRA ± chemo | 6 | 9 | 0.5 |
| APL 9315 | 413 | ATRA ± chemo | 15 | 8 | 1 |
| PETHEMA12 | 123 | ATRA + chemo | 6 | 17 | 0.8 |