Panoply of sickle transgenic mice: description of the features of the most commonly used transgenic sickle mice.
| . | βs% . | αH% . | γ% > 9 wks . | MCH pg/cell . | Retics % . | Hct . | Urine Conc. mOsm . |
|---|---|---|---|---|---|---|---|
| * 8-hour water deprivation | |||||||
| ** 24-hour water deprivation | |||||||
| Abbreviations: MCH, mean corpuscular hemoglobin | |||||||
| C57BL | — | — | — | 14.5 | 2.2 | 48 | 3147**,1688* |
| NY1DD | 75 | 56 | — | 14.1 | 3.2 | 47.0 | 2821** |
| S+S Antilles | 80 | 58 | — | 14.3 | 11.1 | 44.5 | 1302**,* |
| SAD | 19 | 58 | — | 15.1 | 3.6 | 44.0 | 3277** |
| NY1KO γL | 97 | 100 | < 3 | 14.2 | 63.2 | 22.4 | — |
| NY1KO γM | 80 | 100 | 30 | 13.7 | 30.1 | 34.0 | 1176* |
| NY1KO γH | 60 | 100 | 40 | 14.4 | 12.9 | 41.1 | 3285** |
| BERK | > 99 | 100 | < 1 | 9.3 | 36.5 | 28.7 | 898* |
| . | βs% . | αH% . | γ% > 9 wks . | MCH pg/cell . | Retics % . | Hct . | Urine Conc. mOsm . |
|---|---|---|---|---|---|---|---|
| * 8-hour water deprivation | |||||||
| ** 24-hour water deprivation | |||||||
| Abbreviations: MCH, mean corpuscular hemoglobin | |||||||
| C57BL | — | — | — | 14.5 | 2.2 | 48 | 3147**,1688* |
| NY1DD | 75 | 56 | — | 14.1 | 3.2 | 47.0 | 2821** |
| S+S Antilles | 80 | 58 | — | 14.3 | 11.1 | 44.5 | 1302**,* |
| SAD | 19 | 58 | — | 15.1 | 3.6 | 44.0 | 3277** |
| NY1KO γL | 97 | 100 | < 3 | 14.2 | 63.2 | 22.4 | — |
| NY1KO γM | 80 | 100 | 30 | 13.7 | 30.1 | 34.0 | 1176* |
| NY1KO γH | 60 | 100 | 40 | 14.4 | 12.9 | 41.1 | 3285** |
| BERK | > 99 | 100 | < 1 | 9.3 | 36.5 | 28.7 | 898* |