Grades of hematopoietic response to radiation in humans.
| Symptom/Sign . | Degree 1 . | Degree 2 . | Degree 3 . | Degree 4 . |
|---|---|---|---|---|
| Reference values: 1.5–4 × 109/L1, 4–9 × 109/L2, and 140–400 × 109/L3 for lymphocytes, granulocytes, and platelets, respectively. | ||||
| Modified from N Dainiak29 and TM Fliedner, I Friesecke and K Beyrer.13 | ||||
| Lymphocyte changes1 | ≥ 1.5 × 109/L | 1–1.5 × 109/L | 0.5–1 × 109/L | < 0.5 × 109/L |
| Granulocyte changes2 | ≥ 2 × 109/L | 1–2 × 109/L | 0.5–1 × 109/L | < 0.5 × 109/L or initial granulocytosis |
| Thrombocyte changes3 | ≥ 100 × 109/L | 50–100 × 109/L | 20–50 × 109/L | < 20 × 109/L |
| Blood loss | petechiae; easy bruising; normal Hb | mild blood loss with < 10% decrease in Hb | gross blood loss with 10–20% decrease in Hb | spontaneous bleeding or blood loss with > 20% decrease in Hb |
| Symptom/Sign . | Degree 1 . | Degree 2 . | Degree 3 . | Degree 4 . |
|---|---|---|---|---|
| Reference values: 1.5–4 × 109/L1, 4–9 × 109/L2, and 140–400 × 109/L3 for lymphocytes, granulocytes, and platelets, respectively. | ||||
| Modified from N Dainiak29 and TM Fliedner, I Friesecke and K Beyrer.13 | ||||
| Lymphocyte changes1 | ≥ 1.5 × 109/L | 1–1.5 × 109/L | 0.5–1 × 109/L | < 0.5 × 109/L |
| Granulocyte changes2 | ≥ 2 × 109/L | 1–2 × 109/L | 0.5–1 × 109/L | < 0.5 × 109/L or initial granulocytosis |
| Thrombocyte changes3 | ≥ 100 × 109/L | 50–100 × 109/L | 20–50 × 109/L | < 20 × 109/L |
| Blood loss | petechiae; easy bruising; normal Hb | mild blood loss with < 10% decrease in Hb | gross blood loss with 10–20% decrease in Hb | spontaneous bleeding or blood loss with > 20% decrease in Hb |