Tests for Genome-Wide Screening of Chromosomal Abnormalities

• Spectral karyotyping (multicolor fluorescence in situ hybridization)

• Comparative genomic hybridization (research)

Tests Targeting Specific Chromosomal Abnormalities

• PCR (polymerase chain reaction analysis of DNA)

• RT-PCR (reverse transcriptase PCR analysis of RNA)

• Real-time PCR (automated PCR)

• Genotyping for single nucleotide polymorphisms (PCR-SSP)

• Fluorescence in situ hybridization (FISH)

Tests for Gene Expression Profiling

• Global microarrays (research)

• Focused microarrays (research)

• Microarray of amplified RNA from microdissection (research)

Molecular Tests for Minimal Residual Disease Detection

• Nested PCR

• Quantitative real-time PCR (Q-PCR or Q-RT-PCR)