Nonhematologic toxicities with imatinib in newly diagnosed chronic phase chronic myelogenous leukemia (CML) patients.26
| Adverse Event . | All Grades (%) . | Grades 3/4 (%) . |
|---|---|---|
| Superficial edema | 53.2 | 0.9 |
| Nausea | 42.5 | 0.4 |
| Muscle cramps | 35.4 | 1.1 |
| Musculoskeletal pain | 33.6 | 2.7 |
| Rash | 31.9 | 2.0 |
| Fatigue | 30.7 | 1.1 |
| Diarrhea | 30.3 | 1.3 |
| Headache | 28.5 | 0.4 |
| Joint pain | 26.7 | 2.2 |
| Abdominal pain | 23.4 | 2.0 |
| Myalgia | 20.9 | 1.5 |
| Nasopharyngitis | 19.2 | 0 |
| Hemorrhage | 18.9 | 0.7 |
| Dyspepsia | 15.1 | 0 |
| Vomiting | 14.7 | 0.9 |
| Pharyngolaryngeal pain | 14.2 | 0.2 |
| Dizziness | 13.2 | 0.5 |
| Cough | 12.5 | 0.2 |
| URI | 12.5 | 0.2 |
| Pyrexia | 11.8 | 0.5 |
| Weight, increased | 11.6 | 0.7 |
| Insomnia | 11.4 | 0 |
| Depression | 8.9 | 0.5 |
| Constipation | 7.6 | 0.7 |
| Rigors | 6.9 | 0 |
| Anxiety | 6.5 | 0.2 |
| Dyspnea | 6.5 | 1.3 |
| Pruritus | 6.5 | 0.2 |
| Influenza-like illness | 6.4 | 0 |
| Night sweats | 6.4 | 0.2 |
| Anorexia | 4.7 | 0 |
| Sweating, increased | 3.3 | 0 |
| Alopecia | 2.2 | 0 |
| Adverse Event . | All Grades (%) . | Grades 3/4 (%) . |
|---|---|---|
| Superficial edema | 53.2 | 0.9 |
| Nausea | 42.5 | 0.4 |
| Muscle cramps | 35.4 | 1.1 |
| Musculoskeletal pain | 33.6 | 2.7 |
| Rash | 31.9 | 2.0 |
| Fatigue | 30.7 | 1.1 |
| Diarrhea | 30.3 | 1.3 |
| Headache | 28.5 | 0.4 |
| Joint pain | 26.7 | 2.2 |
| Abdominal pain | 23.4 | 2.0 |
| Myalgia | 20.9 | 1.5 |
| Nasopharyngitis | 19.2 | 0 |
| Hemorrhage | 18.9 | 0.7 |
| Dyspepsia | 15.1 | 0 |
| Vomiting | 14.7 | 0.9 |
| Pharyngolaryngeal pain | 14.2 | 0.2 |
| Dizziness | 13.2 | 0.5 |
| Cough | 12.5 | 0.2 |
| URI | 12.5 | 0.2 |
| Pyrexia | 11.8 | 0.5 |
| Weight, increased | 11.6 | 0.7 |
| Insomnia | 11.4 | 0 |
| Depression | 8.9 | 0.5 |
| Constipation | 7.6 | 0.7 |
| Rigors | 6.9 | 0 |
| Anxiety | 6.5 | 0.2 |
| Dyspnea | 6.5 | 1.3 |
| Pruritus | 6.5 | 0.2 |
| Influenza-like illness | 6.4 | 0 |
| Night sweats | 6.4 | 0.2 |
| Anorexia | 4.7 | 0 |
| Sweating, increased | 3.3 | 0 |
| Alopecia | 2.2 | 0 |