Table 1.

Phase II results with imatinib.

Chronic Phase (IFN Failure)22 Accelerated Phase23 Blast Crisis24 
Abbreviations: IFN, interferon; CHR, complete hematologic response; MCR, major cytogenetic response (Ph+ metaphases < 35%); CCR, complete cytogenetic response. 
CHR 95% 34% 8% 
MCR 60% 24% 16% 
CCR 41% 17% 7% 
Disease progression 11% 40% 80% 
Chronic Phase (IFN Failure)22 Accelerated Phase23 Blast Crisis24 
Abbreviations: IFN, interferon; CHR, complete hematologic response; MCR, major cytogenetic response (Ph+ metaphases < 35%); CCR, complete cytogenetic response. 
CHR 95% 34% 8% 
MCR 60% 24% 16% 
CCR 41% 17% 7% 
Disease progression 11% 40% 80% 
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