Predictive value of secretory phospholipase A2(sPLA2) in acute chest syndrome.
| . | Sensitivity (%) . | Specificity (%) . | PPV (%) . | NPV (%) . | Accuracy* (%) . |
|---|---|---|---|---|---|
| Abbreviations: PPV, positive predictive value; NPV, negative predictive value | |||||
| * The number of true positives and true negatives divided by the total number of patients. | |||||
| Reprinted with permission from Styles L et al. Secretory phospholipase A2 predicts impending acute chest syndrome in sickle cell disease. Blood. 2000;96:3276-78. | |||||
| sPLA2 alone | 100 | 67 | 55 | 100 | 76 |
| sPLA2 + fever | 100 | 87 | 75 | 100 | 90 |
| sPLA2 + chest pain | 50 | 80 | 50 | 80 | 71 |
| sPLA2 + respiratory symptoms | 67 | 100 | 100 | 88 | 90 |
| sPLA2 + ausculatory findings | 67 | 100 | 100 | 88 | 90 |
| . | Sensitivity (%) . | Specificity (%) . | PPV (%) . | NPV (%) . | Accuracy* (%) . |
|---|---|---|---|---|---|
| Abbreviations: PPV, positive predictive value; NPV, negative predictive value | |||||
| * The number of true positives and true negatives divided by the total number of patients. | |||||
| Reprinted with permission from Styles L et al. Secretory phospholipase A2 predicts impending acute chest syndrome in sickle cell disease. Blood. 2000;96:3276-78. | |||||
| sPLA2 alone | 100 | 67 | 55 | 100 | 76 |
| sPLA2 + fever | 100 | 87 | 75 | 100 | 90 |
| sPLA2 + chest pain | 50 | 80 | 50 | 80 | 71 |
| sPLA2 + respiratory symptoms | 67 | 100 | 100 | 88 | 90 |
| sPLA2 + ausculatory findings | 67 | 100 | 100 | 88 | 90 |