Table 4.

Comparison of purified clonal CD5+/CD19+ versus fluorescence in situ hybridization (FISH) anomalies in eight patients with stable disease.*

PatientGenetic Anomaly†CD5+/CD19+, %*Abnormal FISH Nuclei, %Delta‡
* CD5+/CD19+ cells were sorted by magnetic bead methods, and their purity was confirmed by flow cytometry. 
†Two anomalies are indicated by a “/” meaning that 1 clone has both genetic defects. 
‡Delta is difference between percentage of purified clonal CLL B cells and numbers of FISH abnormal cells. 
11q/13q 98 70/92 28/6 
13q 99 92 
13q 97 89 
13q 96 83 13 
+12/17p 98 59/71 39/27 
+12 99 65 34 
13q 95 40 55 
13q 96 23 73 
PatientGenetic Anomaly†CD5+/CD19+, %*Abnormal FISH Nuclei, %Delta‡
* CD5+/CD19+ cells were sorted by magnetic bead methods, and their purity was confirmed by flow cytometry. 
†Two anomalies are indicated by a “/” meaning that 1 clone has both genetic defects. 
‡Delta is difference between percentage of purified clonal CLL B cells and numbers of FISH abnormal cells. 
11q/13q 98 70/92 28/6 
13q 99 92 
13q 97 89 
13q 96 83 13 
+12/17p 98 59/71 39/27 
+12 99 65 34 
13q 95 40 55 
13q 96 23 73 
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