Complications of plasma exchange treatment for thrombotic thrombocytopenic purpura (TTP).*
| Complications . | Percentage of Patients with Major Complications . |
|---|---|
| * Adapted from references 4 and 49. Major catheter-related complications included pneumothorax or hemothorax caused by the insertion procedure; sepsis requiring systemic antimicrobial treatment; and thrombosis requiring line replacement or anticoagulant treatment. Major plasma-related complications included hypoxemia or hypotension requiring more than oxygen administration or volume replacement and allergic reactions requiring more than Benadryl and hydrocortisone treatment. No transfusion-transmitted infections were observed. Unintentional plateletpheresis may cause persistent thrombocytopenia, that may be mistaken for continued activity of TTP. | |
| Central venous catheter-related | |
| Insertion procedure | 4% |
| Sepsis | 15% |
| Thrombosis | 10% |
| Plasma-related | |
| Allergic | 4% |
| Infection | 0 |
| Instrument-related | |
| Unintentional plateletpheresis | Unknown |
| Complications . | Percentage of Patients with Major Complications . |
|---|---|
| * Adapted from references 4 and 49. Major catheter-related complications included pneumothorax or hemothorax caused by the insertion procedure; sepsis requiring systemic antimicrobial treatment; and thrombosis requiring line replacement or anticoagulant treatment. Major plasma-related complications included hypoxemia or hypotension requiring more than oxygen administration or volume replacement and allergic reactions requiring more than Benadryl and hydrocortisone treatment. No transfusion-transmitted infections were observed. Unintentional plateletpheresis may cause persistent thrombocytopenia, that may be mistaken for continued activity of TTP. | |
| Central venous catheter-related | |
| Insertion procedure | 4% |
| Sepsis | 15% |
| Thrombosis | 10% |
| Plasma-related | |
| Allergic | 4% |
| Infection | 0 |
| Instrument-related | |
| Unintentional plateletpheresis | Unknown |