International Prognostic Scoring System (IPSS) for myelodysplastic syndrome (MDS).*
| Prognostic Variable . | Survival and AML Evolution Score Value . | ||||
|---|---|---|---|---|---|
| Prognostic Variable . | 0 . | 0.5 . | 1.0 . | 1.5 . | 2.0 . |
| Marrow blasts (%) | < 5 | 5-10 | — | 11-20 | 21-30 |
| Karyotype† | Good | Intermediate | Poor | ||
| Cytopenias‡ | 0-1 | 2-3 | |||
| Prognostic Variable . | Survival and AML Evolution Score Value . | ||||
|---|---|---|---|---|---|
| Prognostic Variable . | 0 . | 0.5 . | 1.0 . | 1.5 . | 2.0 . |
| Marrow blasts (%) | < 5 | 5-10 | — | 11-20 | 21-30 |
| Karyotype† | Good | Intermediate | Poor | ||
| Cytopenias‡ | 0-1 | 2-3 | |||
| Risk Category . | Combined Score . |
|---|---|
| Abbreviations: AML, acute myeloid leukemia. | |
| * Modified from Greenberg P, Cox C, Le Beau MM, et al. International scoring system for evaluating prognosis in myelodysplastic syndromes. Blood. 1997;89:2079-2088. | |
| † Good = normal, Y, del(5q), del(20q); Poor = complex (≥ 3 abnormalities) or chromosome 7 anomalies; Intermediate = other abnormalities. | |
| ‡ Neutrophils < 1800/μL, hemoglobin < 10 g/dL, platelets < 100,000/μL. | |
| Low | 0 |
| Int-1 | 0.5-1.0 |
| Int-2 | 1.5-2.0 |
| High | > 2.5 |
| Risk Category . | Combined Score . |
|---|---|
| Abbreviations: AML, acute myeloid leukemia. | |
| * Modified from Greenberg P, Cox C, Le Beau MM, et al. International scoring system for evaluating prognosis in myelodysplastic syndromes. Blood. 1997;89:2079-2088. | |
| † Good = normal, Y, del(5q), del(20q); Poor = complex (≥ 3 abnormalities) or chromosome 7 anomalies; Intermediate = other abnormalities. | |
| ‡ Neutrophils < 1800/μL, hemoglobin < 10 g/dL, platelets < 100,000/μL. | |
| Low | 0 |
| Int-1 | 0.5-1.0 |
| Int-2 | 1.5-2.0 |
| High | > 2.5 |