Table 1.

Relative increases and decreases of RAD-treated cells in G0G1 and G2/M phases of the cell-cycle of HL and ALCL cells



Cell-cycle profiles
G0/G1, %
S, %
G2/M, %
Cell line
0 nM
10 nM
0 nM
10 nM
0 nM
10 nM
L540cy   44   76   14   8   42   16  
L1236   45   73   13   11   42   16  
KM-H2   41   59   10   10   49   31  
L428   37   62   16   8   47   30  
HD-LM2   56   73   29   18   15   9  
Karpas 299   44   73   10   5   46   22  
FE-PD   48   64   16   11   34   25  
JB6   32   52   15   10   53   38  
SU-DHL
 
41
 
60
 
18
 
14
 
41
 
26
 


Cell-cycle profiles
G0/G1, %
S, %
G2/M, %
Cell line
0 nM
10 nM
0 nM
10 nM
0 nM
10 nM
L540cy   44   76   14   8   42   16  
L1236   45   73   13   11   42   16  
KM-H2   41   59   10   10   49   31  
L428   37   62   16   8   47   30  
HD-LM2   56   73   29   18   15   9  
Karpas 299   44   73   10   5   46   22  
FE-PD   48   64   16   11   34   25  
JB6   32   52   15   10   53   38  
SU-DHL
 
41
 
60
 
18
 
14
 
41
 
26
 

Cell cycles of HL and ALCL cells were analyzed by propidium iodide staining and statistical analysis was performed via ModFit LT program. Untreated cells in G0/G1 and G2/M phase were set arbitrarily at 100% for each cell line.

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